Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.44 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 2/20 | 0.43 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6397014 | 0.84 | MMP13 (0.53) | MMP13MMP2EPHX2FAAHMMP12 | |
| SCHEMBL6401146 | 0.81 | GPR119 (0.59) | MMP13MMP2MMP12MMP14FPR2 | |
| SCHEMBL13198831 | 0.78 | SMN1; SMN2 (0.63) | SMN1; SMN2NPC1RAB9ACYP2C19HTT | |
| SCHEMBL1648387 | 0.77 | SMN1; SMN2 (0.61) | EPHX2SMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL4344327 | 0.77 | SMN1; SMN2 (0.61) | MMP2SMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL1649138 | 0.77 | SMN1; SMN2 (0.61) | EPHX2SMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL3028128 | 0.77 | POLB (0.56) | MMP13MMP2EPHX2FAAHSMN1; SMN2 | |
| SCHEMBL30120062 | 0.76 | SMN1; SMN2 (0.60) | EPHX2SMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL4717723 | 0.76 | SMN1; SMN2 (0.62) | SMN1; SMN2NPC1RAB9ACYP2C19ENPP2 | |
| SCHEMBL1650184 | 0.76 | SMN1; SMN2 (0.60) | MMP2EPHX2FAAHSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050043533-A1 | Process for making alpha-substituted hydroxamic acids | PHARMACIA CORPORATION | 2005-02-24 | — | — | US | disclosed |
| WO-2004091549-A2 | PROCESS FOR MAKING ALPHA-SUBSTITUTED HYDROXAMIC ACIDS | PHARMACIA CORPORATION (US) | 2004-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043533-A1 | Process for making alpha-substituted hydroxamic acids | HAAO, RIMKLA, ASPH | MMP13 104/4885MMP2 1180/4885EPHX2 91/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.