Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.46 |
| ▸ | BCHE | P06276 | 8/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6397400 | 1.00 | GRIN2B (0.46) | GRIN2BBCHEACHESLC18A3ALDH1A1 | |
| SCHEMBL6398778 | 0.86 | KDM4E (0.48) | SLC18A3ALDH1A1KDM4E | |
| SCHEMBL6398787 | 0.86 | KDM4E (0.48) | SLC18A3ALDH1A1KDM4E | |
| SCHEMBL6397839 | 0.78 | ACHE (0.39) | ACHESLC18A3ALDH1A1 | |
| SCHEMBL6396689 | 0.77 | SIGMAR1 (0.37) | ACHEALDH1A1KDM4E | |
| SCHEMBL6397687 | 0.74 | ACHE (0.54) | ACHESLC18A3KDM4E | |
| SCHEMBL6397681 | 0.74 | ACHE (0.54) | ACHESLC18A3KDM4E | |
| SCHEMBL6404810 | 0.71 | ALDH1A1 (0.48) | GRIN2BBCHEACHEALDH1A1GAA | |
| SCHEMBL6404814 | 0.71 | ALDH1A1 (0.48) | GRIN2BBCHEACHEALDH1A1GAA | |
| SCHEMBL6398075 | 0.71 | KDM4E (0.54) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050004092-A1 | Penem derivatives and antimicrobial agent containing the same | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2005-01-06 | — | — | US | disclosed |
| EP-0757051-B1 | PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2003-10-29 | — | — | EP | disclosed |
| EP-0757051-A1 | PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1997-02-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004092-A1 | Penem derivatives and antimicrobial agent containing the same | MRPL21, MRPS2, MRPS28 | GRIN2B 1982/4885BCHE 3543/4885ACHE 2285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.