⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2916301 | 0.79 | SLC6A11 (0.47) | — | |
| SCHEMBL3362598 | 0.65 | — | — | |
| SCHEMBL14506000 | 0.65 | — | — | |
| SCHEMBL14506001 | 0.65 | ALDH1A1 (0.37) | — | |
| SCHEMBL17643080 | 0.64 | SLC6A12 (0.50) | — | |
| SCHEMBL2569289 | 0.64 | — | — | |
| SCHEMBL20343797 | 0.64 | SLC6A12 (0.50) | — | |
| SCHEMBL23829582 | 0.62 | — | — | |
| SCHEMBL7351893 | 0.62 | — | — | |
| Hydrochloric Acid SCHEMBL177340 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014160409-A1 | RBP4 ANTAGONISTS FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION AND STARGARDT DISEASE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2014-10-02 | — | — | WO | claimed |
| CN-102453028-B | Antifungal agent-2- [ (2, 3-dihydro-4H-benzo [ b ] thiopyran-4-ylidene) hydrazono ] -4-oxotetrahydrothia (oxazole) -5-acetic acid derivative | UNIV SHENYANG PHARMACEUTICAL | 2014-07-30 | — | — | CN | claimed |
| EP-1534696-A1 | THERAPEUTIC COMPOUNDS FOR TREATING DYSLIPIDEMIC CONDITIONS | Merck & Co., Inc. (US) | 2005-06-01 | — | — | EP | claimed |
| WO-2004011448-A1 | THERAPEUTIC COMPOUNDS FOR TREATING DYSLIPIDEMIC CONDITIONS | MERCK & CO., INC. (US) | 2004-02-05 | — | — | WO | claimed |
| WO-2003101373-A2 | THIAZOLIDINEDIONE DERIVATIVES IN THERAPEUTIC AND PROPHYLACTIC METHODS | QLT INC. (CA) | 2003-12-11 | — | — | WO | claimed |
| CN-103214414-B | The diamine derivative of opticity and manufacture method thereof | SANKYO CO. (JP) | 2016-02-17 | — | — | CN | disclosed |
| WO-2014160409-A1 | RBP4 ANTAGONISTS FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION AND STARGARDT DISEASE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2014-10-02 | — | — | WO | disclosed |
| CN-102453028-B | Antifungal agent-2- [ (2, 3-dihydro-4H-benzo [ b ] thiopyran-4-ylidene) hydrazono ] -4-oxotetrahydrothia (oxazole) -5-acetic acid derivative | UNIV SHENYANG PHARMACEUTICAL | 2014-07-30 | — | — | CN | disclosed |
| CN-103214414-A | Optically active diamine derivative and process for producing the same | DAIICHI SANKYO CO LTD | 2013-07-24 | — | — | CN | disclosed |
| CN-101263110-B | Optically active diamine derivative and process for producing the same | DAIICHI SANKYO CO LTD | 2013-04-03 | — | — | CN | disclosed |
| CN-1826333-B | Diamine derivatives | DAIICHI SANKYO CO LTD | 2012-12-26 | — | — | CN | disclosed |
| US-6967196-B1 | Sulfonamide compounds and uses thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-11-22 | — | — | US | disclosed |
| EP-1534696-A1 | THERAPEUTIC COMPOUNDS FOR TREATING DYSLIPIDEMIC CONDITIONS | Merck & Co., Inc. (US) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004011448-A1 | THERAPEUTIC COMPOUNDS FOR TREATING DYSLIPIDEMIC CONDITIONS | MERCK & CO., INC. (US) | 2004-02-05 | — | — | WO | disclosed |
| WO-2003101373-A2 | THIAZOLIDINEDIONE DERIVATIVES IN THERAPEUTIC AND PROPHYLACTIC METHODS | QLT INC. (CA) | 2003-12-11 | — | — | WO | disclosed |
| EP-1159263-A1 | NOVEL SULFONAMIDE COMPOUNDS AND USES THEREOF | Merck & Co., Inc. (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000050391-A1 | NOVEL SULFONAMIDE COMPOUNDS AND USES THEREOF | MERCK & CO., INC. (US) | 2000-08-31 | — | — | WO | disclosed |