Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | INPPL1 | O15357 | 3/20 | 0.34 |
| ▸ | INPP5A | Q14642 | 3/20 | 0.34 |
| ▸ | INPP5B | P32019 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6398644 | 0.89 | INPPL1 (0.38) | ADRB1HTR2AADRA1AMIFHTR2B | |
| SCHEMBL6398701 | 0.88 | INPPL1 (0.35) | KDM4EINPPL1INPP5AINPP5BMAPT | |
| SCHEMBL6397576 | 0.85 | SLC22A1 (0.33) | ADRB1HTR2AADRA1AMIFHTR2B | |
| SCHEMBL6397701 | 0.83 | INPPL1 (0.36) | ADRB1HTR2AADRA1AMIFHTR2B | |
| SCHEMBL6398583 | 0.83 | ADRB1 (0.35) | ADRB1HTR2AADRA1AMIFHTR2B | |
| SCHEMBL6404462 | 0.81 | ADRB1 (0.39) | ADRB1HTR2AADRA1AMIFHTR2B | |
| SCHEMBL6395800 | 0.81 | INPPL1 (0.36) | ADRB1HTR2AADRA1AMIFHTR2B | |
| SCHEMBL6404456 | 0.79 | ADRB1 (0.37) | ADRB1HTR2AADRA1AMIFHTR2B | |
| SCHEMBL7617241 | 0.78 | INPPL1 (0.37) | ADRB1HTR2AADRA1AMIFHTR2B | |
| SCHEMBL6396330 | 0.78 | INPPL1 (0.41) | HTR2AHTR2BKDM4EINPPL1INPP5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050187195-A1 | Inhibition of intestinal apical membrane Na/phosphate co-transportation in humans | PEERCE BRIAN E (US) | 2005-08-25 | — | — | US | disclosed |
| US-6787528-B2 | THERAPY FOR KIDNEY DISEASES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2004-09-07 | — | — | US | disclosed |
| US-20030162753-A1 | Inhibition of intestinal apical membrane Na/phosphate co-transportation in humans | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2003-08-28 | — | — | US | disclosed |
| US-20020133036-A1 | Inhibitors of intestinal apical membrane Na/phosphate co-transportation | PEERCE BRIAN E (US) | 2002-09-19 | — | — | US | disclosed |
| US-6355823-B1 | MEMBRANE SUBSTRATE PHOSPHATED FOR DRUGS FOR GASTROINTESTINAL DISORDERS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2002-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187195-A1 | Inhibition of intestinal apical membrane Na/phosphate co-transportation in humans | SLC34A3, SLC34A1, SLC34A2 | ADRB1 1543/4885HTR2A 2756/4885ADRA1A 2552/4885 |
| US-20020133036-A1 | Inhibitors of intestinal apical membrane Na/phosphate co-transportation | SLC10A2, SLC34A3, SLC34A1 | ADRB1 1645/4885HTR2A 2925/4885ADRA1A 2707/4885 |
| US-20030162753-A1 | Inhibition of intestinal apical membrane Na/phosphate co-transportation in humans | SLC34A3, SLC34A1, SLC34A2 | ADRB1 1543/4885HTR2A 2756/4885ADRA1A 2552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.