Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sorbitol SCHEMBL3029801 | 0.95 | PRKCA (0.50) | PRKCATDP1LMNAL3MBTL1PDE4A | |
| Triacetin SCHEMBL29242627 | 0.94 | PRKCA (0.47) | PRKCATDP1LMNAARGAA | |
| Triacetin SCHEMBL890839 | 0.85 | PRKCA (0.46) | PRKCATDP1ARGAA | |
| Triacetin SCHEMBL1531419 | 0.85 | PRKCA (0.46) | PRKCATDP1LMNAARGAA | |
| SCHEMBL349280 | 0.84 | LMNA (0.48) | TDP1LMNAL3MBTL1PDE4AUSP2 | |
| Triacetin SCHEMBL22160048 | 0.84 | PRKCA (0.57) | PRKCATDP1AR | |
| SCHEMBL5909539 | 0.84 | LMNA (0.48) | TDP1LMNAL3MBTL1PDE4AUSP2 | |
| SCHEMBL347295 | 0.84 | LMNA (0.48) | TDP1LMNAL3MBTL1PDE4AUSP2 | |
| Triacetin SCHEMBL821340 | 0.84 | TDP1 (0.56) | PRKCATDP1LMNAARGAA | |
| Triacetin SCHEMBL3870 | 0.84 | TDP1 (0.56) | PRKCATDP1LMNAARGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050232957-A1 | Compositions and methods for moisturizing skin | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 2005-10-20 | — | — | US | claimed |
| US-20050232957-A1 | Compositions and methods for moisturizing skin | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE | 2005-10-20 | — | — | US | disclosed |
| EP-0999844-A1 | PRETREATING HYPERLIPIDEMIC INDIVIDUALS WITH A FLUSH INHIBITING AGENT PRIOR TO NICOTINIC ACID THERAPY | KOS PHARMACEUTICALS, INC. (US) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999006052-A1 | METHODS OF PRETREATING HYPERLIPIDEMIC INDIVIDUALS WITH A FLUSH INHIBITING AGENT PRIOR TO THE START OF SINGLE DAILY DOSE NICOTINIC ACID THERAPY TO REDUCE FLUSHING PROVOKED BY NICOTINIC ACID | KOS PHARMACEUTICALS, INC. (US) | 1999-02-11 | — | — | WO | disclosed |
| EP-0596437-A2 | Biodegradable polymer blend composition | Bio-tec Biologische Naturverpackungen GmbH (DE) | 1994-05-11 | — | — | EP | disclosed |