Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | TLR2 | O60603 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2090432 | 0.92 | SPHK1 (0.42) | SPHK2SPHK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL6337958 | 0.89 | TSHR (0.34) | SPHK2SPHK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL26997903 | 0.83 | TSHR (0.38) | SPHK2SPHK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL17909259 | 0.79 | TSHR (0.46) | TSHRTLR2HSD17B10PLA2G2C | |
| SCHEMBL27559738 | 0.79 | CYP1A2 (0.35) | SPHK2SPHK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL17909058 | 0.79 | TSHR (0.46) | TSHRTLR2HSD17B10PLA2G2C | |
| SCHEMBL17908953 | 0.79 | TSHR (0.46) | TSHRTLR2HSD17B10PLA2G2C | |
| SCHEMBL27819968 | 0.78 | GAA (0.40) | CYP1A2CYP3A4CYP2C19L3MBTL1TSHR | |
| SCHEMBL26724992 | 0.77 | PAOX (0.40) | SPHK2SPHK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL10879931 | 0.77 | ALDH1A1 (0.52) | TSHRTLR2HSD17B10PLA2G2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6967196-B1 | Sulfonamide compounds and uses thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-11-22 | — | — | US | disclosed |