Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | PLA2G2C | Q5R387 | 3/20 | 0.35 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26724992 | 0.94 | PAOX (0.40) | TSHRALDH1A1TDP1ACHEPAOX | |
| SCHEMBL26724993 | 0.92 | PAOX (0.43) | TSHRALDH1A1PAOXCES2PLA2G2C | |
| SCHEMBL8379954 | 0.86 | ALDH1A1 (0.41) | TSHRALDH1A1TDP1ACHEPAOX | |
| SCHEMBL6398251 | 0.83 | SPHK2 (0.37) | TSHRPLA2G2CSPHK2SPHK1CYP1A2 | |
| SCHEMBL23729612 | 0.82 | FAAH (0.43) | TSHRPAOX | |
| SCHEMBL26708614 | 0.82 | FAAH (0.43) | TSHRPAOX | |
| SCHEMBL1921248 | 0.81 | ALDH1A1 (0.50) | TSHRALDH1A1TDP1ACHEPAOX | |
| SCHEMBL17909058 | 0.79 | TSHR (0.46) | TSHRALDH1A1TDP1PLA2G2CHSD17B10 | |
| SCHEMBL17909259 | 0.79 | TSHR (0.46) | TSHRALDH1A1TDP1PLA2G2CHSD17B10 | |
| SCHEMBL27559738 | 0.79 | CYP1A2 (0.35) | TSHRTDP1PLA2G2CSPHK2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873291-B2 | Quinoline cGAS antagonist compounds | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2024-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11873291-B2 | Quinoline cGAS antagonist compounds | CGAS, GLS2, GLS | TSHR 2355/4885ALDH1A1 4236/4885TDP1 69/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.