Nitrobenzene

Nitrobenzene

SCHEMBL6398341

CCCCCCC.O=[N+]([O-])c1ccccc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.67
LMNA P02545 3/20 0.67
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
CRHBP P24387 2/20 0.52
CRHR2 Q13324 2/20 0.52
ATM Q13315 1/20 0.52
TLR9 Q9NR96 1/20 0.52
MAPT P10636 3/20 0.51
KCNH2 Q12809 1/20 0.51
MGLL Q99685 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.48
HTT P42858 1/20 0.48
HPGD P15428 1/20 0.47
ALOX12 P18054 1/20 0.47
TSHR P16473 1/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2C19 P33261 2/20 0.46
CYP2D6 P10635 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrobenzene SCHEMBL9324297 0.98 ALDH1A1 (0.70) ALDH1A1LMNAMEN1KMT2AL3MBTL1
Nitrobenzene SCHEMBL28135666 0.94 LMNA (0.70) ALDH1A1LMNAMEN1KMT2AL3MBTL1
Octadecylamine SCHEMBL10745393 0.91 ALDH1A1 (0.55) ALDH1A1LMNAMEN1KMT2AL3MBTL1
Nitrobenzene SCHEMBL22440636 0.89 ALDH1A1 (0.53) ALDH1A1LMNAMEN1KMT2AL3MBTL1
Nitrobenzene SCHEMBL28084244 0.89 ALDH1A1 (0.57) ALDH1A1LMNAMEN1KMT2AL3MBTL1
Nitrobenzene SCHEMBL8208664 0.89 ALDH1A1 (0.57) ALDH1A1LMNAMEN1KMT2AL3MBTL1
Nitrobenzene SCHEMBL28306081 0.89 ALDH1A1 (0.57) ALDH1A1LMNAMEN1KMT2AL3MBTL1
Dodecanoate SCHEMBL28651197 0.88 PPARG (0.55) ALDH1A1LMNAMEN1KMT2ATSHR
Palmitic Acid SCHEMBL27955225 0.88 PPARG (0.55) ALDH1A1LMNAMEN1KMT2ATSHR
Nitrobenzene SCHEMBL28245209 0.87 ALDH1A1 (0.55) ALDH1A1LMNAMEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6939923-B2 Resin for solid phase synthesis ROHM AND HAAS COMPANY (US) 2005-09-06 US disclosed
EP-1452538-A1 Method of manufacturing T-20 and T-1249 peptides at commercial scale, and T-20 and T-1249 compositions related thereto ROHM AND HAAS COMPANY (US) 2004-09-01 EP disclosed
EP-1403290-A1 Resin for solid phase synthesis Rohm and Haas (US) 2004-03-31 EP disclosed
EP-1394196-A1 Resin for solid phase synthesis ROHM AND HAAS COMPANY (US) 2004-03-03 EP disclosed