Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 6/20 | 0.49 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ATR | Q13535 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4814655 | 0.79 | HDAC1 (0.45) | L3MBTL1ATRMAPTAKT1 | |
| SCHEMBL14146402 | 0.79 | TARBP2 (0.35) | TARBP2PDCD4L3MBTL1MEN1KMT2A | |
| SCHEMBL14146392 | 0.78 | NPSR1 (0.40) | L3MBTL1ATRALDH1A1NPSR1KDM4E | |
| SCHEMBL30615060 | 0.78 | ATR (0.53) | L3MBTL1ATRMAPTAKT1 | |
| SCHEMBL14146412 | 0.78 | TARBP2 (0.34) | TARBP2PDCD4L3MBTL1MEN1KMT2A | |
| SCHEMBL18181481 | 0.78 | TARBP2 (0.34) | TARBP2PDCD4L3MBTL1MEN1KMT2A | |
| SCHEMBL6504455 | 0.76 | TARBP2 (0.74) | TARBP2PDCD4ALDH1A1NPSR1KDM4E | |
| SCHEMBL3180689 | 0.74 | L3MBTL1 (0.61) | L3MBTL1NPSR1MAPTRECQL | |
| SCHEMBL18181482 | 0.74 | ADORA2A (0.37) | TARBP2PDCD4L3MBTL1MEN1KMT2A | |
| SCHEMBL6385812 | 0.74 | PPARA (0.57) | KDM4EHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050026929-A1 | Novel phenyl derivatives as inducers of apoptosis | AXYS PHARMACEUTICALS, INC. (US) | 2005-02-03 | — | — | US | disclosed |
| WO-2003090680-A2 | NOVEL PHENYL DERIVATIVES AS INDUCERS OF APOPTOSIS | AXYS PHARMACEUTICALS, INC. (US) | 2003-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050026929-A1 | Novel phenyl derivatives as inducers of apoptosis | BAX, BAD, CASP3 | TARBP2 3928/4885PDCD4 31/4885L3MBTL1 1537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.