Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 5/20 | 0.40 |
| ▸ | DRD4 | P21917 | 5/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6402198 | 0.78 | PLD1 (0.50) | KDM4ECYP2C19ALDH1A1MAPTDRD2 | |
| SCHEMBL4760428 | 0.76 | DYRK1A (0.49) | KDM4ECYP2C19ALDH1A1LMNAMAPT | |
| SCHEMBL5485755 | 0.76 | KDM4E (0.53) | KDM4ECYP2C19ALDH1A1LMNAMAPT | |
| SCHEMBL18239359 | 0.76 | DYRK1A (0.49) | KDM4ECYP2C19ALDH1A1LMNAMAPT | |
| SCHEMBL26700624 | 0.76 | DYRK1A (0.49) | KDM4ECYP2C19ALDH1A1LMNAMAPT | |
| SCHEMBL30743834 | 0.76 | KDM4E (0.53) | KDM4ECYP2C19ALDH1A1LMNAMAPT | |
| SCHEMBL13703144 | 0.76 | DYRK1A (0.49) | KDM4ECYP2C19ALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL18228230 | 0.74 | DYRK1A (0.48) | KDM4ECYP2C19ALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL26086988 | 0.74 | DYRK1A (0.48) | KDM4ECYP2C19ALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL26086991 | 0.74 | DYRK1A (0.48) | KDM4ECYP2C19ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050037919-A1 | Metallocenes and catalyst compositions derived therefrom | EXXONMOBIL CHEMICAL PATENTS INC. | 2005-02-17 | — | — | US | disclosed |
| US-20050004092-A1 | Penem derivatives and antimicrobial agent containing the same | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2005-01-06 | — | — | US | disclosed |
| EP-0757051-B1 | PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2003-10-29 | — | — | EP | disclosed |
| US-6051569-A | 1'S, 5R, 6R-carbapenem derivatives and antimicrobial agents comprising the same | SUNTORY LIMITED (JP) | 2000-04-18 | — | — | US | disclosed |
| EP-0826687-A1 | Carbapenem derivatives and antimicrobial agents comprising the same | SUNTORY LIMITED (JP) | 1998-03-04 | — | — | EP | disclosed |
| EP-0774465-A1 | Penem derivatives and antimicrobial agents containing the same | SUNTORY LIMITED (JP) | 1997-05-21 | — | — | EP | disclosed |
| EP-0757051-A1 | PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1997-02-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004092-A1 | Penem derivatives and antimicrobial agent containing the same | MRPL21, MRPS2, MRPS28 | KDM4E 1902/4885CYP2C19 3170/4885ALDH1A1 1862/4885 |
| US-20050037919-A1 | Metallocenes and catalyst compositions derived therefrom | HMOX1, RTF1, OPRM1 | KDM4E 4555/4885CYP2C19 2209/4885ALDH1A1 376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.