Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitroanilide SCHEMBL5718352 | 0.77 | L3MBTL1 (0.50) | CTSDSMN1; SMN2GAAALDH1A1MAPT | |
| SCHEMBL31732365 | 0.77 | ALDH1A1 (0.38) | SMN1; SMN2GAAHTTALDH1A1MAPT | |
| Nitroanilide SCHEMBL6001 | 0.77 | L3MBTL1 (0.50) | CTSDSMN1; SMN2GAAALDH1A1MAPT | |
| SCHEMBL578924 | 0.76 | CYP11B1 (0.50) | SMN1; SMN2ALDH1A1MAPTPOLBKMT2A | |
| Nitroanilide SCHEMBL29021277 | 0.75 | L3MBTL1 (0.48) | CTSDSMN1; SMN2GAAALDH1A1MAPT | |
| Nitroanilide SCHEMBL4541850 | 0.75 | L3MBTL1 (0.48) | CTSDSMN1; SMN2GAAALDH1A1MAPT | |
| Nitroanilide SCHEMBL29195338 | 0.75 | L3MBTL1 (0.48) | CTSDSMN1; SMN2GAAALDH1A1MAPT | |
| Nitroanilide SCHEMBL3094185 | 0.75 | L3MBTL1 (0.48) | CTSDSMN1; SMN2GAAALDH1A1MAPT | |
| Nitroanilide SCHEMBL20876421 | 0.75 | L3MBTL1 (0.48) | CTSDSMN1; SMN2GAAALDH1A1MAPT | |
| Nitroanilide SCHEMBL30436028 | 0.75 | L3MBTL1 (0.48) | CTSDSMN1; SMN2GAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6960568-B2 | Nucleosides and related processes, pharmaceutical compositions and methods | YALE UNIVERSITY (US) | 2005-11-01 | — | — | US | disclosed |
| US-20050239726-A1 | Novel nucleosides and related processes, pharmaceutical compositions and methods | YALE UNIVERSITY (US) | 2005-10-27 | — | — | US | disclosed |
| US-20040116362-A1 | Novel nucleosides and related processes, pharmaceutical compositions and methods | YALE UNIVERSITY | 2004-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239726-A1 | Novel nucleosides and related processes, pharmaceutical compositions and methods | ADAR, DCTD, ADA | CTSD 1725/4885MDM2 3091/4885SMN1; SMN2 2480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.