Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 5/20 | 0.56 |
| ▸ | ACHE | P22303 | 2/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | DRD1 | P21728 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | DRD5 | P21918 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10532680 | 0.89 | HTR1A (0.56) | HTR1ADRD4DRD2DRD1HTR2A | |
| SCHEMBL7488440 | 0.87 | HTR1A (0.58) | HTR1ADRD4DRD2DRD1HTR2A | |
| SCHEMBL26108581 | 0.82 | HTR1A (0.65) | CYP3A4CYP2C9HTR1ADRD4DRD2 | |
| SCHEMBL26492991 | 0.82 | HTR1A (0.65) | CYP3A4CYP2C9HTR1ADRD4DRD2 | |
| SCHEMBL23252522 | 0.81 | HTR1A (0.53) | MEN1KMT2AHTR1ADRD4DRD2 | |
| Hydrochloric Acid SCHEMBL26108377 | 0.81 | DRD2 (0.63) | HTR1ADRD2DRD1HTR2ADRD3 | |
| SCHEMBL5652648 | 0.81 | HTR1A (0.55) | MEN1KMT2AHTR1ADRD4DRD2 | |
| SCHEMBL7488861 | 0.81 | MEN1 (0.56) | MEN1KMT2AHTR1ADRD4DRD2 | |
| SCHEMBL1307809 | 0.81 | POLB (0.53) | MEN1KMT2AHTR1ADRD4DRD2 | |
| SCHEMBL3910170 | 0.81 | LMNA (0.57) | MEN1KMT2AHTR1AACHEDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050004092-A1 | Penem derivatives and antimicrobial agent containing the same | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2005-01-06 | — | — | US | disclosed |
| EP-0757051-B1 | PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2003-10-29 | — | — | EP | disclosed |
| US-5712270-A | TREATING PARKINSON*S DISEASE, DOWN*S SYNDROME, AND ALZHEIMER*S DISEASE WITH COGNITION ACTIVATORS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-01-27 | — | — | US | disclosed |
| EP-0757051-A1 | PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1997-02-05 | — | — | EP | disclosed |
| US-5510478-A | TREATMENT OF NEUROLOGICAL ILLNESSES RELATED TO CHOLINERGIC DEFICIENCY; ALZHEIMERS'S DISEASE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-04-23 | — | — | US | disclosed |
| US-4873331-A | ANTIDEPRESSANTS, ANXIOLYTIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-10-10 | — | — | US | disclosed |
| US-4797489-A | ANTIDEPRESSANTS, ANXIOLYTIC AGENTS | AMERICAN HOME PRODUCTS CORP. (US) | 1989-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004092-A1 | Penem derivatives and antimicrobial agent containing the same | MRPL21, MRPS2, MRPS28 | MEN1 3773/4885KMT2A 2222/4885CYP3A4 3356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.