Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31377051 | 0.88 | CASP3 (0.85) | CASP3ALDH1A1POLBRXFP1NPSR1 | |
| SCHEMBL170913 | 0.88 | CASP3 (0.85) | CASP3ALDH1A1POLBRXFP1NPSR1 | |
| Methane SCHEMBL4623788 | 0.86 | CASP3 (0.82) | CASP3ALDH1A1POLBRXFP1NPSR1 | |
| SCHEMBL13442855 | 0.81 | CASP3 (1.00) | CASP3ALDH1A1POLBRXFP1NPSR1 | |
| SCHEMBL11843816 | 0.80 | CA12 (0.48) | CASP3ALDH1A1CA12CA9PKM | |
| SCHEMBL11845945 | 0.80 | GLS (0.53) | CASP3ALDH1A1NPSR1CA12CA9 | |
| SCHEMBL11848701 | 0.77 | TDP1 (0.51) | MAPTKMT2ACYP2C19RAB9ASMN1; SMN2 | |
| SCHEMBL2359299 | 0.77 | CASP3 (0.46) | CASP3ALDH1A1CA12CA9CA2 | |
| SCHEMBL11840055 | 0.77 | TDP1 (0.56) | MAPTCYP2C19RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL11445227 | 0.77 | CYP1B1 (0.52) | ALDH1A1CA12CA9LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57042743-A | — | — | None | — | — | JP | disclosed |
| JP-57042744-A | — | — | None | — | — | JP | disclosed |
| US-6946458-B2 | N-thiolated beta-lactams: novel antibacterial agents for methicillin-resistant Staphylococcus aureus | UNIVERSITY OF SOUTH FLORIDA (US) | 2005-09-20 | — | — | US | disclosed |
| US-20030191108-A1 | N-thiolated beta-lactams: novel antibacterial agents for methicillin-resistant staphylococcus aureus | SOUTH FLORIDA, UNIVERSITY OF | 2003-10-09 | — | — | US | disclosed |
| US-4427439-A | Composition for plant growth regulation | GAF CORPORATION (US) | 1984-01-24 | — | — | US | disclosed |
| JP-S5742744-A | RUBBER COMPOSITION | YOKOHAMA RUBBER CO LTD:THE | 1982-03-10 | — | — | JP | disclosed |
| JP-S5742743-A | RUBBER COMPOSITION | YOKOHAMA RUBBER CO LTD:THE | 1982-03-10 | — | — | JP | disclosed |
| JP-S05742743-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191108-A1 | N-thiolated beta-lactams: novel antibacterial agents for methicillin-resistant staphylococcus aureus | AAAS, TST, NRDC | CASP3 1725/4885ALDH1A1 2378/4885POLB 2073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.