Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 5/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CDC25A | P30304 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
| ▸ | CDC25C | P30307 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924383 | 0.80 | CDK2 (0.33) | CA9CA2CA12MEN1KMT2A | |
| SCHEMBL12059117 | 0.78 | CA9 (0.40) | CA9CA2CA12MEN1KMT2A | |
| SCHEMBL26048161 | 0.74 | CA9 (0.33) | CA9CA2CA12MEN1KMT2A | |
| SCHEMBL26048155 | 0.74 | CA9 (0.33) | CA9CA2CA12MEN1KMT2A | |
| SCHEMBL30480962 | 0.74 | CA9 (0.33) | CA9CA2CA12MEN1KMT2A | |
| SCHEMBL23518159 | 0.74 | CA9 (0.41) | CA9CA2CA12MEN1KMT2A | |
| SCHEMBL24132855 | 0.74 | CA9 (0.33) | CA9CA2CA12MEN1KMT2A | |
| SCHEMBL12041250 | 0.74 | CA9 (0.33) | CA9CA2CA12MEN1KMT2A | |
| SCHEMBL5034447 | 0.73 | SLC6A2 (0.34) | CA9CA2 | |
| SCHEMBL26225205 | 0.73 | SLC6A2 (0.34) | CA9CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190077797-A1 | PROCESSES FOR PREPARING 2-DIHALO RIBOLACTONES | EMORY UNIVERSITY | 2019-03-14 | — | — | US | claimed |
| EP-1300395-B1 | 4-SUBSTITUTED PIPERIDINE COMPOUND | EISAI R&D MAN CO LTD (JP) | 2009-09-02 | — | — | EP | claimed |
| US-7378425-B2 | (1-Indanone)-(1,2,3,6-tetrahydropyridine) compounds | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2008-05-27 | — | — | US | claimed |
| EP-1491531-B1 | (1-INDANONE)-(1,2,3,6-TETRAHYDROPYRIDINE) DERIVATIVE | EISAI R&D MAN CO LTD (JP) | 2007-12-26 | — | — | EP | claimed |
| US-6906083-B2 | 4-substituted piperidine compound | EISAI CO., LTD. (JP) | 2005-06-14 | — | — | US | claimed |
| US-20050124642-A1 | (1-Indanone)-(1,2,3,6-tetrahydropyridine) compounds | EISAI CO., LTD. (JP) | 2005-06-09 | — | — | US | claimed |
| CN-1184203-C | 1-benzyl-4- [ (5, 6-dimethoxy-2-fluoro-1-indanone) -2-yl ] methylpiperidine | EISAI CO LTD (JP) | 2005-01-12 | — | — | CN | claimed |
| CN-1454209-A | 1-benzyl-4- [ (5, 6-dimethoxy-2-fluoro-1-indanone) -2-yl ] methylpiperidine | EISAI CO LTD (JP) | 2003-11-05 | — | — | CN | claimed |
| US-20030166925-A1 | 4-Substituted piperidine compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2003-09-04 | — | — | US | claimed |
| EP-1316549-A1 | 1-BENZYL-4- (5,6-DIMETHOXY-2-FLUORO-1-INDANON)-2-YL] METHYLPIPERIDINE | Eisai Co., Ltd. (JP) | 2003-06-04 | — | — | EP | claimed |
| EP-1300395-A1 | 4-SUBSTITUTED PIPERIDINE COMPOUND | Eisai Co., Ltd. (JP) | 2003-04-09 | — | — | EP | claimed |
| EP-0885867-B1 | Process and intermediate compounds for the preparation of pesticidal fluoroolefin compounds | BASF AG (DE) | 2001-10-24 | — | — | EP | claimed |
| US-6277866-B1 | 1-benzyl-4[(5,6-dimethoxy-2-fluoro-1-indanon)-2-yl]methylpiperidine | EISAI CO., LTD. (JP) | 2001-08-21 | — | — | US | claimed |
| US-5973190-A | Process and intermediate compounds for the preparation of pesticidal fluoroolefin compounds | AMERICAN CYANAMID COMPANY (US) | 1999-10-26 | — | — | US | claimed |
| EP-0885867-A1 | Process and intermediate compounds for the preparation of pesticidal fluoroolefin compounds | American Cyanamid Company (US) | 1998-12-23 | — | — | EP | claimed |
| EP-4735445-A1 | KRAS MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2026-05-06 | — | — | EP | disclosed |
| US-12552754-B1 | Leflutrozole compositions of matter and processes for preparation | ReproNovo SA (CH) | 2026-02-17 | — | — | US | disclosed |
| US-5246952-A | Antitumor agents | CIBA-GEIGY CORPORATION (US) | 1993-09-21 | — | — | US | disclosed |
| US-5227393-A | estrogen-dependent diseases, anticancer | CIBA-GEIGY CORPORATION (US) | 1993-07-13 | — | — | US | disclosed |
| US-5153358-A | Process for the preparation of alpha-alkylated alpha-amino acids and alpha-halogenated alpha-amino acids | ABBOTT LABORATORIES (US) | 1992-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190077797-A1 | PROCESSES FOR PREPARING 2-DIHALO RIBOLACTONES | DERA, DPYD, DUS2 | CA9 2497/4885CA2 3122/4885CA12 3581/4885 |
| US-12552754-B1 | Leflutrozole compositions of matter and processes for preparation | CYP19A1, CYP17A1, SHBG | CA9 872/4885CA2 2489/4885CA12 1626/4885 |
| US-20030166925-A1 | 4-Substituted piperidine compound | ACHE, CHRM4, CHRM1 | CA9 895/4885CA2 178/4885CA12 2066/4885 |
| US-20050124642-A1 | (1-Indanone)-(1,2,3,6-tetrahydropyridine) compounds | SIGMAR1, CHRM1, ACHE | CA9 4076/4885CA2 1340/4885CA12 4358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.