Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6003686 | 0.84 | TBXAS1 (0.44) | DPP4MAOAMAOBRIPK1PIN1 | |
| SCHEMBL6003677 | 0.84 | TBXAS1 (0.44) | DPP4MAOAMAOBRIPK1PIN1 | |
| SCHEMBL6005325 | 0.84 | TBXAS1 (0.44) | DPP4MAOAMAOBRIPK1PIN1 | |
| SCHEMBL31067929 | 0.84 | TBXAS1 (0.44) | DPP4MAOAMAOBRIPK1PIN1 | |
| SCHEMBL15881633 | 0.83 | LDHA (0.51) | — | |
| SCHEMBL15881661 | 0.83 | LDHA (0.55) | — | |
| SCHEMBL15881697 | 0.83 | EPHX1 (0.54) | EPHX1 | |
| SCHEMBL2739147 | 0.81 | DPP4 (0.48) | DPP4DPP7MAOAMAOBMAPK8 | |
| SCHEMBL370923 | 0.81 | DPP4 (0.45) | DPP4DPP7MAOAMAOBRIPK1 | |
| SCHEMBL18492879 | 0.81 | DPP4 (0.48) | DPP4DPP7MAOAMAOBMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6967196-B1 | Sulfonamide compounds and uses thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-11-22 | — | — | US | disclosed |