Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 3/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 3/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6400197 | 0.82 | ESR1 (0.41) | ACHEMEN1KMT2ACNR1CNR2 | |
| SCHEMBL726409 | 0.77 | ESR1 (0.42) | ACHEMEN1KMT2ACNR1CNR2 | |
| SCHEMBL23581823 | 0.75 | ACHE (0.48) | ACHEESR1ESR2ALDH1A1HDAC4 | |
| SCHEMBL726368 | 0.75 | ESR1 (0.43) | ACHEMEN1KMT2ACNR1CNR2 | |
| SCHEMBL9656072 | 0.73 | ALDH1A1 (0.50) | ACHEESR1ESR2ALDH1A1HDAC4 | |
| SCHEMBL8840942 | 0.71 | ALDH1A1 (0.44) | ACHEESR1ESR2PGRALOX12 | |
| SCHEMBL21801277 | 0.70 | RPS6KA3 (0.41) | ACHEMEN1KMT2ACNR1CNR2 | |
| SCHEMBL31179852 | 0.70 | RPS6KA3 (0.41) | ACHEMEN1KMT2ACNR1CNR2 | |
| SCHEMBL18468531 | 0.69 | PDK2 (0.54) | PGRPDK2L3MBTL1 | |
| SCHEMBL24129070 | 0.69 | PDK2 (0.46) | PGRPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6849706-B1 | Copolyetherimides | GENERAL ELECTRIC COMPANY (US) | 2005-02-01 | — | — | US | claimed |