Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.37 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6400202 | 0.82 | ACHE (0.40) | ESR1ESR2CNR2CNR1ACHE | |
| SCHEMBL29577228 | 0.81 | PGR (0.39) | ESR1ESR2ALDH1A1CYP3A4MAPT | |
| SCHEMBL28077328 | 0.76 | CNR2 (0.48) | CNR2CNR1ACHETSHRMEN1 | |
| SCHEMBL29993063 | 0.75 | ESR1 (0.44) | ESR1ESR2ACHEPGRHDAC4 | |
| SCHEMBL11401705 | 0.75 | ESR1 (0.44) | ESR1ESR2ACHEPGRHDAC4 | |
| SCHEMBL8064831 | 0.73 | ESR1 (0.47) | ESR1ESR2ACHEMEN1KMT2A | |
| SCHEMBL379394 | 0.72 | ESR1 (0.46) | ESR1ESR2ACHEMEN1KMT2A | |
| SCHEMBL31490381 | 0.72 | ESR1 (0.46) | ESR1ESR2ACHEMEN1KMT2A | |
| SCHEMBL2640042 | 0.72 | ESR1 (0.46) | ESR1ESR2ACHEMEN1KMT2A | |
| SCHEMBL8840942 | 0.71 | ALDH1A1 (0.44) | ESR1ESR2ACHEKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6849706-B1 | Copolyetherimides | GENERAL ELECTRIC COMPANY (US) | 2005-02-01 | — | — | US | claimed |