Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6400375 | 0.81 | KCNN4 (0.49) | KCNN4CYP3A4LMNAHSP90AA1CYP19A1 | |
| SCHEMBL8591922 | 0.81 | KCNN4 (0.49) | KCNN4CYP3A4LMNAHSP90AA1CYP19A1 | |
| SCHEMBL405869 | 0.79 | KCNN4 (0.46) | KCNN4CYP3A4LMNAHSP90AA1CYP19A1 | |
| SCHEMBL14398864 | 0.78 | KCNN4 (0.43) | KCNN4CYP3A4LMNAHSP90AA1CYP19A1 | |
| SCHEMBL29727285 | 0.78 | KCNN4 (0.43) | KCNN4CYP3A4LMNAHSP90AA1CYP19A1 | |
| SCHEMBL1507033 | 0.78 | KCNN4 (0.43) | KCNN4CYP3A4LMNAHSP90AA1CYP19A1 | |
| SCHEMBL8637490 | 0.77 | MAPT (0.37) | KCNN4CYP3A4LMNAHSP90AA1CYP19A1 | |
| SCHEMBL8636719 | 0.76 | KCNN4 (0.44) | KCNN4CYP3A4LMNAHSP90AA1CYP19A1 | |
| SCHEMBL8780648 | 0.74 | HDAC6 (0.43) | KCNN4CYP3A4LMNACYP2C19HDAC6 | |
| SCHEMBL441530 | 0.73 | ALDH1A1 (0.42) | KCNN4CYP3A4LMNAHSP90AA1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577712-B1 | FUNGICIDAL 4-THIOXOOXAZOLIDIN-2-ONES AND 4-IMINOOXAZOLINDIN-2-ONES | DU PONT (US) | 1998-07-29 | — | — | EP | disclosed |
| EP-0577712-A1 | FUNGICIDAL 4-THIOXOOXAZOLIDIN-2-ONES AND 4-IMINOOXAZOLINDIN-2-ONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-01-12 | — | — | EP | disclosed |
| WO-1992016515-A1 | FUNGICIDAL 4-THIOXOOXAZOLIDIN-2-ONES AND 4-IMINOOXAZOLINDIN-2-ONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-10-01 | — | — | WO | disclosed |