Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 4/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.39 |
| ▸ | KDM5A | P29375 | 2/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | EBP | Q15125 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11586877 | 1.00 | TSHR (0.48) | TSHRDNM1S1PR2S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL5595409 | 0.98 | DNM1 (0.48) | TSHRDNM1S1PR2S1PR1S1PR3 | |
| SCHEMBL5613764 | 0.98 | TSHR (0.50) | TSHRDNM1S1PR2S1PR1S1PR3 | |
| SCHEMBL13609722 | 0.91 | TSHR (0.52) | TSHRDNM1S1PR2S1PR1S1PR3 | |
| SCHEMBL16892353 | 0.89 | CHRM2 (0.42) | TSHRS1PR2S1PR1S1PR3S1PR5 | |
| Water SCHEMBL9299486 | 0.83 | DNM1 (0.63) | TSHRDNM1S1PR2S1PR1S1PR3 | |
| Water SCHEMBL29199994 | 0.83 | DNM1 (0.63) | TSHRDNM1S1PR2S1PR1S1PR3 | |
| SCHEMBL21077931 | 0.83 | TSHR (0.48) | TSHRDNM1S1PR2S1PR1S1PR3 | |
| SCHEMBL3456909 | 0.81 | CHRM2 (0.46) | TSHRS1PR2S1PR1S1PR3S1PR5 | |
| SCHEMBL9797780 | 0.81 | TSHR (0.43) | TSHRCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1213999-C | Aliphatic amino carboxylic and aminophosphonic acids, amino nitriles and amino tetrazoles as cell rescue agents | UNIV OF SASKATCHEWAN TECHNOLOG (CA) | 2005-08-10 | — | — | CN | claimed |
| US-20050159393-A1 | Aliphatic amino carboxylic and amino phosphonic acids, amino nitriles and amino tetrazoles as cellular rescue agents | UNIVERSITY OF SASKATCHEWAN TECHNOLOGIES INC. (CA) | 2005-07-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159393-A1 | Aliphatic amino carboxylic and amino phosphonic acids, amino nitriles and amino tetrazoles as cellular rescue agents | CHAMP1, PYCR1, PRMT5 | TSHR 1907/4885DNM1 1307/4885S1PR2 1230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.