Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 6/20 | 0.44 |
| ▸ | ESR1 | P03372 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAPDH | P04406 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | BCR | P11274 | 2/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7200530 | 0.84 | ESR2 (0.45) | ESR2ESR1ALDH1A1HPGDNPC1 | |
| SCHEMBL4808028 | 0.83 | MEN1 (0.45) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9418173 | 0.81 | ESR2 (0.43) | ESR2ESR1ALDH1A1HPGDNPC1 | |
| SCHEMBL5887304 | 0.79 | ABL1 (0.47) | ALDH1A1HPGDNPC1GAPDHRAB9A | |
| SCHEMBL4014642 | 0.77 | GSTP1 (0.48) | ESR2ESR1ALDH1A1HPGDNPC1 | |
| SCHEMBL5887228 | 0.76 | MEN1 (0.40) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4808761 | 0.76 | MEN1 (0.40) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5887233 | 0.73 | LTA4H (0.49) | ALDH1A1NPC1GAPDHRAB9ASMN1; SMN2 | |
| SCHEMBL5887216 | 0.73 | AURKA (0.45) | NPC1RAB9ASMN1; SMN2ABL1ABCB1 | |
| SCHEMBL6942856 | 0.73 | BACE1 (0.45) | ESR2ESR1ALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6955851-B2 | Hydroxyaryl phosphine oxides, glycidyl ethers and epoxy compositions, composites and laminates derived therefrom | PABU SERVICES, INC. (US) | 2005-10-18 | — | — | US | disclosed |
| US-6733698-B2 | Mixture of mono-, bis- and tris-(hydroxyaryl) phosphine oxides useful to make polyglycidyl ethers or in epoxy compositions | PABU SERVICES, INC. | 2004-05-11 | — | — | US | disclosed |