Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4988485 | 0.84 | PIM1 (0.43) | GSTP1HDAC4HDAC2HDAC8ESR2 | |
| SCHEMBL667985 | 0.79 | ALDH1A1 (0.38) | ALOX5KDM4EGPR84ADORA2AADORA1 | |
| SCHEMBL6400913 | 0.77 | ESR2 (0.44) | ESR2ESR1ALOX5KDM4EHSD17B1 | |
| SCHEMBL4808028 | 0.77 | MEN1 (0.45) | KDM4EGPR84CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL11613220 | 0.77 | GSTP1 (0.43) | GSTP1HDAC4HDAC2HDAC8ESR2 | |
| SCHEMBL5887304 | 0.77 | ABL1 (0.47) | HDAC4HDAC2HDAC8ALOX5KDM4E | |
| SCHEMBL1234940 | 0.75 | ALDH1A1 (0.37) | ALDH1A1HPGD | |
| SCHEMBL11569950 | 0.74 | TAAR1 (0.38) | ESR2DHFRALOX5KDM4EGPR84 | |
| SCHEMBL11368788 | 0.72 | ALOX5 (0.52) | GSTP1HDAC4HDAC2HDAC8ESR2 | |
| SCHEMBL4622720 | 0.72 | GSTP1 (0.42) | GSTP1HDAC4HDAC2HDAC8ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009082157-A2 | ARYL AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | DOOSAN CORPORATION (KR) | 2009-07-02 | — | — | WO | disclosed |