Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MPI | P34949 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10670045 | 1.00 | BACE1 (0.45) | BACE1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7200530 | 0.89 | ESR2 (0.45) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL667985 | 0.78 | ALDH1A1 (0.38) | BACE1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6605331 | 0.77 | GPR84 (0.40) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL1322927 | 0.75 | TRPM4 (0.41) | BACE1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1193247 | 0.75 | TRPM4 (0.41) | BACE1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9640308 | 0.75 | IDO1 (0.43) | ALOX5HSD17B10HSD17B1HSD17B2ESR2 | |
| SCHEMBL10501308 | 0.73 | BACE1 (0.40) | BACE1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9857390 | 0.73 | RAB9A (0.40) | BACE1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6400913 | 0.73 | ESR2 (0.44) | ALDH1A1KDM4EMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268584-A4 | COMPOSITIONS AND METHODS FOR SELECTIVELY BINDING AMINES OR AMINO ACID ENANTIOMERS OVER THEIR COUNTER-ENANTIOMERS | IBC ADVANCED TECH INC (US) | 2003-06-18 | — | — | EP | disclosed |
| EP-1268584-A1 | COMPOSITIONS AND METHODS FOR SELECTIVELY BINDING AMINES OR AMINO ACID ENANTIOMERS OVER THEIR COUNTER-ENANTIOMERS | IBC ADVANCED TECHNOLOGIES, INC. (US) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001068729-A1 | COMPOSITIONS AND METHODS FOR SELECTIVELY BINDING AMINES OR AMINO ACID ENANTIOMERS OVER THEIR COUNTER-ENANTIOMERS | IBC ADVANCED TECHNOLOGIES, INC. (US) | 2001-09-20 | — | — | WO | disclosed |