SCHEMBL6400917

SCHEMBL6400917

Cc1cc2c(cc1C)N(c1ccc(-c3ccccc3)cc1)c1cc3ccccc3cc1N2c1ccc(-c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.43
FAAH O00519 1/20 0.43
MGLL Q99685 1/20 0.43
PDE10A Q9Y233 1/20 0.36
MYC P01106 1/20 0.36
OXTR P30559 1/20 0.36
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
BRD4 O60885 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
AVPR1A P37288 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
APP P05067 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13886640 0.91 FAAH (0.50) PDE6DFAAHMGLLESR1ESR2
SCHEMBL6400284 0.85 CYP2A6 (0.43) MGLLMEN1KMT2ANPC1RAB9A
SCHEMBL18905741 0.85 FAAH (0.46) PDE6DFAAHMGLLBRD4MEN1
SCHEMBL6404589 0.81 HSP90AA1 (0.52) MEN1KMT2ANPC1RAB9A
SCHEMBL19343001 0.80 ESR1 (0.42) FAAHMGLLESR1ESR2MEN1
SCHEMBL6401392 0.79 CYP2A6 (0.48) MGLLMYCMEN1KMT2ANPC1
SCHEMBL30076220 0.79 CYP2A6 (0.48) MGLLMYCMEN1KMT2ANPC1
SCHEMBL30076295 0.78 MGLL (0.42) MGLLMYCESR1MEN1KMT2A
SCHEMBL21272270 0.78 MGLL (0.42) MGLLMYCESR1MEN1KMT2A
SCHEMBL16281051 0.78 MGLL (0.42) MGLLMYCESR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6919140-B2 Organic electroluminescent devices with high luminance EASTMAN KODAK COMPANY (US) 2005-07-19 US disclosed
US-20050014018-A1 Organic electroluminescent devices with high luminance EASTMAN KODAK COMPANY 2005-01-20 US disclosed