SCHEMBL6400928

SCHEMBL6400928

NS(=O)(=O)c1cccc([N+](=O)[O-])c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 9/20 1.00
CA5A P35218 3/20 1.00
KMT2A Q03164 2/20 0.72
GAA P10253 1/20 0.72
HTT P42858 1/20 0.72
CA1 P00915 8/20 0.66
CA9 Q16790 6/20 0.66
CA12 O43570 5/20 0.66
CA13 Q8N1Q1 2/20 0.64
CA5B Q9Y2D0 2/20 0.62
CA14 Q9ULX7 2/20 0.62
CA3 P07451 1/20 0.62
CA4 P22748 1/20 0.62
CA6 P23280 1/20 0.62
CA7 P43166 1/20 0.62
MMP1 P03956 1/20 0.62
MMP2 P08253 1/20 0.62
MMP9 P14780 1/20 0.62
MMP8 P22894 1/20 0.62
MMP13 P45452 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31527772 1.00 CA2 (1.00) CA2CA5AKMT2AGAAHTT
SCHEMBL189037 1.00 CA2 (1.00) CA2CA5AKMT2AGAAHTT
Iodide SCHEMBL28547164 0.98 CA2 (0.96) CA2CA5AKMT2AGAAHTT
Hydrochloric Acid SCHEMBL27515852 0.98 CA2 (0.96) CA2CA5AKMT2AGAAHTT
SCHEMBL17647048 0.98 CA2 (0.96) CA2CA5AKMT2AGAAHTT
Bromide SCHEMBL25252561 0.98 CA2 (0.96) CA2CA5AKMT2AGAAHTT
SCHEMBL28485485 0.92 CA2 (0.84) CA2CA5AKMT2AGAAHTT
SCHEMBL29431934 0.92 CA2 (0.84) CA2CA5AKMT2AGAAHTT
Alcohol SCHEMBL6121614 0.90 CA2 (0.81) CA2CA5AKMT2AGAAHTT
SCHEMBL28106126 0.86 VCAM1 (0.77) CA2CA5AKMT2AGAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115843297-A Compounds as BCL-2 inhibitors 重庆复创医药研究有限公司 2023-03-24 CN disclosed
EP-2620508-B1 METHOD AND DEVICE FOR DETECTING NUCLEIC ACID, AND KIT KANEKA CORP (JP) 2017-09-06 EP disclosed
EP-2682480-B1 NUCLEIC ACID DETECTION METHOD, AND DEVICE AND KIT FOR USE IN SAME KANEKA CORP (JP) 2017-05-03 EP disclosed
US-9476836-B2 Nucleic acid detection method, and device and kit for use in same KANEKA CORPORATION (JP) 2016-10-25 US disclosed
US-20160209332-A1 NUCLEIC ACID DETECTION METHOD, AND DEVICE AND KIT FOR USE IN SAME KANEKA CORP (JP) 2016-07-21 US disclosed
US-9273174-B2 Nucleic acid detection method, and device and kit for use in same KANEKA CORPORATION (JP) 2016-03-01 US disclosed
US-9097718-B2 Method and device for detecting nucleic acid, and kit KANEKA CORPORATION (JP) 2015-08-04 US disclosed
US-20140058043-A1 NUCLEIC ACID DETECTION METHOD, AND DEVICE AND KIT FOR USE IN SAME KANEKA CORPORATION (JP) 2014-02-27 US disclosed
US-20130252341-A1 METHOD AND DEVICE FOR DETECTING NUCLEIC ACID, AND KIT KANEKA CORPORATION (JP) 2013-09-26 US disclosed
EP-2620508-A1 METHOD AND DEVICE FOR DETECTING NUCLEIC ACID, AND KIT Kaneka Corporation (JP) 2013-07-31 EP disclosed
US-20050153408-A1 7-substituted-2-tetralone or bisulfite adduct is reduced microorganism (Candida) to optically active 7-substituted-2-tetralol;sulfonyl group is introduced to hydroxy group to form optically active 7-substituted-2-sulfonyloxytetralin; nitrogen substituent is introduced via ammonia; industrial scale KANEKA CORPORATION (JP) 2005-07-14 US disclosed
EP-1457570-A1 PROCESS FOR PREPARATION OF 2-AMINOTETRALIN DERIVATIVES AND INTERMEDIATES THEREOF KANEKA CORPORATION (JP) 2004-09-15 EP disclosed