SCHEMBL189037

SCHEMBL189037

NS(=O)(=O)c1cccc([N+](=O)[O-])c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 9/20 1.00
CA5A P35218 3/20 1.00
KMT2A Q03164 2/20 0.72
GAA P10253 1/20 0.72
HTT P42858 1/20 0.72
CA1 P00915 8/20 0.66
CA9 Q16790 6/20 0.66
CA12 O43570 5/20 0.66
CA13 Q8N1Q1 2/20 0.64
CA5B Q9Y2D0 2/20 0.62
CA14 Q9ULX7 2/20 0.62
CA3 P07451 1/20 0.62
CA4 P22748 1/20 0.62
CA6 P23280 1/20 0.62
CA7 P43166 1/20 0.62
MMP1 P03956 1/20 0.62
MMP2 P08253 1/20 0.62
MMP9 P14780 1/20 0.62
MMP8 P22894 1/20 0.62
MMP13 P45452 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31527772 1.00 CA2 (1.00) CA2CA5AKMT2AGAAHTT
SCHEMBL6400928 1.00 CA2 (1.00) CA2CA5AKMT2AGAAHTT
Iodide SCHEMBL28547164 0.98 CA2 (0.96) CA2CA5AKMT2AGAAHTT
Hydrochloric Acid SCHEMBL27515852 0.98 CA2 (0.96) CA2CA5AKMT2AGAAHTT
SCHEMBL17647048 0.98 CA2 (0.96) CA2CA5AKMT2AGAAHTT
Bromide SCHEMBL25252561 0.98 CA2 (0.96) CA2CA5AKMT2AGAAHTT
SCHEMBL28485485 0.92 CA2 (0.84) CA2CA5AKMT2AGAAHTT
SCHEMBL29431934 0.92 CA2 (0.84) CA2CA5AKMT2AGAAHTT
Alcohol SCHEMBL6121614 0.90 CA2 (0.81) CA2CA5AKMT2AGAAHTT
SCHEMBL28106126 0.86 VCAM1 (0.77) CA2CA5AKMT2AGAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 778 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114614058-B Thin-layer composite proton exchange membrane and preparation method and application thereof 中国石油化工股份有限公司 2024-05-07 CN claimed
CN-115637149-B Perovskite quantum dot diffusion plate and preparation method thereof 无锡极电光能科技有限公司 2024-04-05 CN claimed
CN-114308121-B Phosphine oxide catalyst and preparation method and application thereof 浙江工业大学 2024-02-23 CN claimed
CN-115521783-B Method for passivating perovskite quantum dot surface defects 无锡极电光能科技有限公司 2023-11-10 CN claimed
CN-108947931-B Thiazole amide compound, preparation method thereof, pharmaceutical composition and application 中国科学院上海有机化学研究所 2023-07-07 CN claimed
CN-115637149-A Perovskite quantum dot diffusion plate and preparation method thereof 无锡极电光能科技有限公司 2023-01-24 CN claimed
CN-115521783-A Method for passivating surface defects of perovskite quantum dots 无锡极电光能科技有限公司 2022-12-27 CN claimed
CN-114614058-A Thin-layer composite proton exchange membrane and preparation method and application thereof 中国石油化工股份有限公司 2022-06-10 CN claimed
CN-114432903-A Composite membrane with acid resistance and preparation method and application thereof 中国石油化工股份有限公司 2022-05-06 CN claimed
CN-114308121-A Phosphine oxide catalyst and preparation method and application thereof 浙江工业大学 2022-04-12 CN claimed
US-20080200454-A1 CARBON-LINKED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S SUNESIS PHARMACEUTICALS, INC. 2008-08-21 US claimed
EP-1931645-A2 N- (3-AMINO-QUINOXALIN-2-YL) -SULFONAMIDE DERIVATIVES AND THEIR USE AS PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS Exelixis, Inc. (US) 2008-06-18 EP claimed
CN-101048383-A Gonadotropin releasing hormone receptor antagonists WYETH CORP (US) 2007-10-03 CN claimed
WO-2007108742-A1 NOVEL TETRALINS AS 5-HT6 MODULATORS ASTRAZENECA AB (SE) 2007-09-27 WO claimed
WO-2007044729-A2 N- (3-AMINO-QUINOXALIN-2-YL) -SULFONAMIDE DERIVATIVES AND THEIR USE AS PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS EXELIXIS, INC. (US) 2007-04-19 WO claimed
US-6337368-B1 WATER INSOLUBLE CARRIERS WITH P-NITROBENZOIC ACID, AROMATIC AMINES, AMIDES, SULFONAMIDES AND HYDRAZIDES KANEKA CORPORATION (JP) 2002-01-08 US claimed
CN-1247537-A Sulfonamide compounds having 5-HT receptor activity KNOLL AG (DE) 2000-03-15 CN claimed
EP-0117080-B1 SKIN TREATMENT COMPOSITION UNILEVER PLC (GB) 1992-04-08 EP claimed
EP-0270293-A1 Substituted 3-nitrobenzenesulfonamides useful as adjuncts in radiation therapy MERCK & CO. INC. (US) 1988-06-08 EP claimed
EP-0117080-A2 Skin treatment composition UNILEVER PLC (GB) 1984-08-29 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080200454-A1 CARBON-LINKED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S CTSS, CTSK, CTSZ CA2 413/4885CA5A 2019/4885KMT2A 4390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.