Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 7/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25254402 | 0.83 | HDAC1 (0.33) | — | |
| SCHEMBL9263112 | 0.83 | PLA2G2A (0.47) | MEN1KMT2A | |
| SCHEMBL9273783 | 0.83 | PLA2G2A (0.47) | MEN1KMT2A | |
| SCHEMBL2973653 | 0.80 | LDHA (0.37) | MEN1KMT2AKDM4EPTGS1 | |
| SCHEMBL5518087 | 0.79 | ALDH1A1 (0.43) | KDM4EHSD17B10 | |
| SCHEMBL9955513 | 0.77 | TP53 (0.36) | CNR2GAAMEN1KMT2AKDM4E | |
| SCHEMBL9269021 | 0.76 | PLA2G2A (0.47) | MEN1KMT2A | |
| SCHEMBL9274404 | 0.73 | PLA2G2A (0.49) | MEN1KMT2A | |
| SCHEMBL9956059 | 0.71 | KMT2A (0.33) | CYP1A2CYP2C19GAAMEN1CYP2C9 | |
| SCHEMBL9269950 | 0.71 | PLA2G2A (0.49) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6861418-B2 | 4-aryl substituted indolinones | SUGEN, INC. (US) | 2005-03-01 | — | — | US | disclosed |