⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6398802 | 0.83 | NT5E (0.36) | — | |
| SCHEMBL6398837 | 0.77 | IMPDH2 (0.33) | — | |
| SCHEMBL6397633 | 0.76 | ADORA1 (0.31) | — | |
| SCHEMBL6398234 | 0.72 | — | — | |
| SCHEMBL6402871 | 0.68 | — | — | |
| SCHEMBL6396244 | 0.68 | — | — | |
| SCHEMBL6401808 | 0.62 | LMNA (0.33) | — | |
| SCHEMBL6403546 | 0.62 | LMNA (0.45) | — | |
| SCHEMBL6398878 | 0.60 | ADORA3 (0.40) | — | |
| SCHEMBL6431046 | 0.59 | P2RY2 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050059817-A1 | Methods for synthesizing nucleosides, nucleoside derivatives and non-nucleoside derivatives | SIRNA THERAPEUTICS, INC. (US) | 2005-03-17 | — | — | US | disclosed |
| US-20020150936-A1 | Methods for synthesizing nucleosides, nucleoside derivatives and non-nucleoside derivatives | RIBOZYME PHARMACEUTICALS, INC. | 2002-10-17 | — | — | US | disclosed |