SCHEMBL6401979

SCHEMBL6401979

Nc1cccc(-c2nc3cc(N)ccc3s2)c1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.77
RAB9A P51151 8/20 0.77
KDM4E B2RXH2 7/20 0.77
SMN1; SMN2 Q16637 7/20 0.77
NPC1 O15118 6/20 0.77
GAA P10253 5/20 0.77
NFKB1 P19838 5/20 0.77
NFKB2 Q00653 5/20 0.77
RELA Q04206 5/20 0.77
ALDH1A1 P00352 4/20 0.77
MEN1 O00255 4/20 0.77
KMT2A Q03164 4/20 0.77
POLB P06746 4/20 0.77
TP53 P04637 4/20 0.77
GLA P06280 3/20 0.77
HPGD P15428 3/20 0.77
HSD17B10 Q99714 3/20 0.77
PKM P14618 2/20 0.77
CASP1 P29466 2/20 0.77
CASP7 P55210 2/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11656487 0.92 MAPT (0.74) MAPTRAB9AKDM4ESMN1; SMN2NPC1
SCHEMBL2245118 0.88 MAPT (0.81) MAPTRAB9AKDM4ESMN1; SMN2NPC1
SCHEMBL19149498 0.88 KDM4E (0.65) MAPTRAB9AKDM4ESMN1; SMN2NPC1
SCHEMBL2244190 0.88 MAPT (0.65) MAPTRAB9AKDM4ESMN1; SMN2NPC1
SCHEMBL30776283 0.87 RAB9A (1.00) MAPTRAB9AKDM4ESMN1; SMN2NPC1
SCHEMBL2242693 0.87 RAB9A (1.00) MAPTRAB9AKDM4ESMN1; SMN2NPC1
SCHEMBL11749206 0.87 MAPT (1.00) MAPTRAB9AKDM4ESMN1; SMN2NPC1
SCHEMBL29918176 0.84 MAPT (1.00) MAPTRAB9AKDM4ESMN1; SMN2NPC1
SCHEMBL6399498 0.84 MAPT (1.00) MAPTRAB9AKDM4ESMN1; SMN2NPC1
SCHEMBL3190375 0.84 MAPT (0.71) MAPTRAB9AKDM4ESMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104829837-B A kind of method using magnetic particle sensing to add hot preparation soluble polyimide 黑龙江省科学院石油化学研究院 2017-01-04 CN claimed
CN-104829837-B A kind of method using magnetic particle sensing to add hot preparation soluble polyimide 黑龙江省科学院石油化学研究院 2017-01-04 CN disclosed
US-20050170077-A1 Adhesion method SHIPLEY COMPANY, L.L.C. (US) 2005-08-04 US disclosed
US-20040161545-A1 Adhesion method SHIPLEY COMPANY, L.L.C. 2004-08-19 US disclosed
EP-0464371-A1 Polyamic acid structures, and methods of fabrication thereof International Business Machines Corporation (US) 1992-01-08 EP disclosed
US-5004627-A Polyimides for mold release ETHYL CORPORATION (US) 1991-04-02 US disclosed
EP-0192937-B1 FLEXIBLE POLYIMIDE MULTILAYER LAMINATE Akzo Patente GmbH (DE) 1990-10-24 EP disclosed
EP-0249744-B1 PROCESS FOR MAKING POLYIMIDE-METAL LAMINATES AKZO N.V. (NL) 1989-10-11 EP disclosed
EP-0167020-B1 FLEXIBLE POLYIMIDE MULTILAYER LAMINATE Akzo Patente GmbH (DE) 1988-11-23 EP disclosed
US-4746561-A Polyimide-containing cover layer for a printed circuit element AKZO N.V. (NL) 1988-05-24 US disclosed
EP-0249744-A1 Process for making polyimide-metal laminates AKZO N.V. (NL) 1987-12-23 EP disclosed
EP-0116297-B1 POLYIMIDE LAMINATE WITH PEEL-RESISTANCE AND METHOD OF MANUFACTURING IT Akzo GmbH (DE) 1987-12-02 EP disclosed
US-4705720-A FOR PRINTED CIRCUITS AKZO NV (NL) 1987-11-10 US disclosed
US-4699841-A PRINTED CIRCUITS AKZO NV (NL) 1987-10-13 US disclosed
US-4675246-A DIRECT BONDING WITH SUBSTRATE AND POLYIMIDE AKZO NV (NL) 1987-06-23 US disclosed
EP-0167020-A2 Flexible polyimide multilayer laminate Akzo Patente GmbH (DE) 1986-01-08 EP disclosed
US-4522880-A EXTRUSION ON SUBSTRATE, THEN CURING AKZONA INCORPORATED (US) 1985-06-11 US disclosed
EP-0116297-A2 Polyimide laminate with peel-resistance and method of manufacturing it Akzo GmbH (DE) 1984-08-22 EP disclosed
US-4024125-A Dis-azo pigments deriving from bis-diazotized diamino-2-phenyl-benzazolones HOECHST AKTIENGESELLSCHAFT (DT) 1977-05-17 US disclosed