Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4845129 | 0.87 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7768824 | 0.79 | KMT2A (0.42) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL4845114 | 0.79 | CACNA1B (0.48) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6403388 | 0.77 | KMT2A (0.44) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4836119 | 0.72 | KMT2A (0.46) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5353390 | 0.71 | KMT2A (0.56) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5344798 | 0.70 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5753566 | 0.70 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5350729 | 0.70 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5355130 | 0.70 | BRD4 (0.40) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6903119-B1 | Amino acid derivatives and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-06-07 | — | — | US | disclosed |