Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 4/20 | 0.36 |
| ▸ | MMP1 | P03956 | 3/20 | 0.36 |
| ▸ | MMP3 | P08254 | 3/20 | 0.36 |
| ▸ | MMP7 | P09237 | 3/20 | 0.36 |
| ▸ | MMP9 | P14780 | 3/20 | 0.36 |
| ▸ | MMP8 | P22894 | 3/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | YAP1 | P46937 | 1/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7774665 | 0.85 | MEN1 (0.43) | KMT2AMEN1ALDH1A1LMNAPOLB | |
| SCHEMBL7110470 | 0.83 | MEN1 (0.43) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL7110901 | 0.83 | MEN1 (0.43) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL7105591 | 0.83 | MEN1 (0.43) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL7105628 | 0.83 | MEN1 (0.45) | KMT2AMEN1ALDH1A1LMNAPOLB | |
| SCHEMBL7112266 | 0.80 | MEN1 (0.40) | KMT2AMEN1ALDH1A1LMNAPOLB | |
| SCHEMBL6402029 | 0.79 | MEN1 (0.49) | KMT2AMEN1ALDH1A1LMNAPOLB | |
| SCHEMBL7110494 | 0.75 | CACNA1B (0.50) | KMT2AMEN1CACNA1BYAP1 | |
| SCHEMBL7768814 | 0.75 | CACNA1B (0.39) | KMT2AMEN1ALDH1A1POLBMMP13 | |
| SCHEMBL7110461 | 0.75 | CACNA1B (0.44) | KMT2AMEN1CACNA1BYAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097929-A1 | AMINO ACID DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-05-09 | — | — | EP | disclosed |