Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4845129 | 0.80 | ALDH1A1 (0.45) | KMT2AMEN1ALDH1A1LMNAMMP1 | |
| SCHEMBL4845114 | 0.80 | CACNA1B (0.48) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6402029 | 0.77 | MEN1 (0.49) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7768824 | 0.71 | KMT2A (0.42) | KMT2AMEN1ALDH1A1LMNAMMP1 | |
| SCHEMBL5353390 | 0.68 | KMT2A (0.56) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5347270 | 0.68 | KMT2A (0.58) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5347274 | 0.68 | KMT2A (0.58) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4836117 | 0.67 | CACNA1B (0.51) | KMT2AMEN1ALDH1A1LMNAMMP1 | |
| SCHEMBL4836119 | 0.67 | KMT2A (0.46) | KMT2AMEN1ALDH1A1LMNAMMP1 | |
| SCHEMBL4844855 | 0.66 | CACNA1B (0.50) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050090558-A1 | Compositions and methods of using compositions with accelerated lymphocyte homing immunosuppressive properties | WELFIDE CORPORATION | 2005-04-28 | — | — | US | disclosed |
| US-20040092603-A1 | Compositions and methods of using compositions with accelerated lymphocyte homing immunosuppressive properties | MITSUBISHI PHARMA CORPORATION (JP) | 2004-05-13 | — | — | US | disclosed |
| US-6667025-B2 | Suppressing immune response in a mammal comprising accelerating lymphocyte homing (ALH) to any of mesenteric or peripheral lymph tissues or Peyer's patches by administering an ALH-immunosuppressive compound | MITSUBISHI PHARMA CORPORATION (JP) | 2003-12-23 | — | — | US | disclosed |
| US-20020102279-A1 | COMPOSITIONS AND METHODS OF USING COMPOSITIONS WITH ACCELERATED LYMPHOCYTE HOMING IMMUNOSUPPRESSIVE PROPERTIES | MITSUBISHI PHARMA CORPORATION (JP) | 2002-08-01 | — | — | US | disclosed |
| US-6004565-A | Administering fingolimod hydrochloride | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020102279-A1 | COMPOSITIONS AND METHODS OF USING COMPOSITIONS WITH ACCELERATED LYMPHOCYTE HOMING IMMUNOSUPPRESSIVE PROPERTIES | CD47, S1PR5, S1PR3 | KMT2A 1897/4885MEN1 1598/4885ALDH1A1 4227/4885 |
| US-20040092603-A1 | Compositions and methods of using compositions with accelerated lymphocyte homing immunosuppressive properties | CD47, S1PR5, S1PR3 | KMT2A 1897/4885MEN1 1598/4885ALDH1A1 4227/4885 |
| US-20050090558-A1 | Compositions and methods of using compositions with accelerated lymphocyte homing immunosuppressive properties | CD47, S1PR5, S1PR3 | KMT2A 1897/4885MEN1 1598/4885ALDH1A1 4227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.