Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | ALPG | P10696 | 2/20 | 0.60 |
| ▸ | CDC25A | P30304 | 2/20 | 0.60 |
| ▸ | CDC25B | P30305 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6404073 | 0.97 | ALDH1A1 (0.63) | ALDH1A1HPGDMEN1KMT2AALPG | |
| SCHEMBL6404543 | 0.92 | MAPT (0.64) | ALDH1A1HPGDMEN1KMT2ACDC25A | |
| SCHEMBL6404742 | 0.90 | LMNA (0.58) | ALDH1A1HPGDMEN1KMT2AALPG | |
| SCHEMBL6405226 | 0.86 | TP53 (0.56) | ALDH1A1HPGDMEN1KMT2AALPG | |
| SCHEMBL6408488 | 0.86 | ALDH1A1 (0.70) | ALDH1A1HPGDMEN1KMT2AALPG | |
| SCHEMBL6404213 | 0.86 | MEN1 (0.62) | ALDH1A1HPGDMEN1KMT2APKM | |
| SCHEMBL6409643 | 0.85 | TP53 (0.65) | ALDH1A1HPGDMEN1KMT2AALPG | |
| SCHEMBL6403434 | 0.85 | ALDH1A1 (0.63) | ALDH1A1HPGDMEN1KMT2AALPG | |
| SCHEMBL6403527 | 0.85 | TSHR (0.66) | ALDH1A1HPGDPKMLMNAL3MBTL1 | |
| SCHEMBL3300655 | 0.84 | ALPG (0.53) | ALDH1A1HPGDMEN1KMT2AALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | ALDH1A1 720/4885HPGD 835/4885MEN1 3562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.