Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CDC25A | P30304 | 3/20 | 0.53 |
| ▸ | CDC25B | P30305 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6404213 | 0.94 | MEN1 (0.62) | TP53MDM2THRBMEN1KMT2A | |
| SCHEMBL6404543 | 0.92 | MAPT (0.64) | TP53MDM2MEN1KMT2ALMNA | |
| SCHEMBL6403977 | 0.91 | LMNA (0.56) | TP53MDM2THRBMEN1KMT2A | |
| SCHEMBL6405086 | 0.90 | MAPT (0.61) | TP53LMNATSHRALOX15ALDH1A1 | |
| SCHEMBL5332243 | 0.90 | ALDH1A1 (0.67) | TP53MDM2THRBMEN1KMT2A | |
| SCHEMBL6404294 | 0.88 | MEN1 (0.53) | TP53MDM2THRBMEN1KMT2A | |
| SCHEMBL6404073 | 0.87 | ALDH1A1 (0.63) | TP53MEN1KMT2ALMNAMAPK1 | |
| SCHEMBL6403249 | 0.86 | MAPK1 (0.57) | TP53MEN1KMT2ALMNATSHR | |
| SCHEMBL6402175 | 0.85 | ALDH1A1 (0.60) | TP53MEN1KMT2ALMNATSHR | |
| SCHEMBL5331381 | 0.85 | TP53 (0.74) | TP53MDM2THRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | TP53 1524/4885MDM2 1609/4885THRB 1479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.