Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | IDH2 | P48735 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6401198 | 0.85 | NPC1 (0.37) | NPC1MAPTRAB9APRMT6IDH1 | |
| SCHEMBL6401175 | 0.80 | NPC1 (0.43) | NPC1MAPTRAB9APRMT6IDH1 | |
| SCHEMBL16202042 | 0.78 | MAPT (0.52) | NPC1MAPTRAB9APRMT6IDH1 | |
| SCHEMBL3480443 | 0.73 | NPC1 (0.41) | NPC1MAPTRAB9APRMT6IDH1 | |
| SCHEMBL16911724 | 0.71 | NPC1 (0.51) | NPC1MAPTRAB9APRMT6IDH1 | |
| SCHEMBL2161196 | 0.71 | PRMT6 (0.49) | NPC1MAPTRAB9APRMT6IDH1 | |
| SCHEMBL8259527 | 0.69 | NPC1 (0.58) | NPC1MAPTRAB9APRMT6IDH1 | |
| SCHEMBL16911209 | 0.69 | NPC1 (0.49) | NPC1MAPTRAB9APRMT6NPSR1 | |
| SCHEMBL1836548 | 0.68 | HPGD (0.47) | NPC1MAPTRAB9APRMT6NPSR1 | |
| SCHEMBL4608788 | 0.68 | NPC1 (0.45) | NPC1MAPTRAB9APRMT6IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050107383-A1 | 3-ARYLPHENYL SULFIDE DERIVATIVE AND INSECTICIDE AND MITICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-05-19 | — | — | US | disclosed |
| US-6509354-B1 | Insecticides and miticides containing the 3-arylphenyl sulfide derivatives as an active ingredient. | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107383-A1 | 3-ARYLPHENYL SULFIDE DERIVATIVE AND INSECTICIDE AND MITICIDE | CBR3, MSRB3, CYP1B1 | NPC1 2264/4885MAPT 4460/4885RAB9A 1903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.