Xanthone

Xanthone

SCHEMBL6402455

Cc1ccc2c(c1)Cc1ccccc1[S+]2[O-].O=c1c2ccccc2oc2ccccc12

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 7/20 0.44
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
GLA P06280 1/20 0.44
CYP3A4 P08684 1/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
PGAM1 P18669 1/20 0.44
CASP1 P29466 1/20 0.44
CASP7 P55210 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HSD17B10 Q99714 1/20 0.44
NPC1 O15118 4/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
RAB9A P51151 3/20 0.39
LMNA P02545 2/20 0.38
TP53 P04637 1/20 0.38
RET P07949 1/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Xanthone SCHEMBL9175425 0.88 MAOA (0.56) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL82772 0.83 ALDH1A1 (0.34) KDM4EALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL15411118 0.83 ALDH1A1 (0.34) KDM4EALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL11661520 0.75 DRD1 (0.40) MAOAMAOB
SCHEMBL11159542 0.75 METAP1 (0.36) KDM4EALDH1A1CYP3A4MAPTSMN1; SMN2
Xanthone SCHEMBL6159522 0.74 TTR (0.40) KDM4EALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL1037618 0.74 ALDH1A1 (0.34) KDM4EALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL13932526 0.72 METAP1 (0.36) KDM4EALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL352535 0.72 MAOA (0.67) MAOAKDM4EALDH1A1GLACYP3A4
Xanthone SCHEMBL11252075 0.72 MAOA (0.67) MAOAKDM4EALDH1A1GLACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050142357-A1 High strength pressure sensitive adhesive ADHESIVES RESEARCH, INC. (US) 2005-06-30 US disclosed
WO-2004011568-A2 HIGH STRENGTH PRESSURE SENSITIVE ADHESIVE ADHESIVES RESEARCH, INC. (US) 2004-02-05 WO disclosed
US-6566466-B1 Reacting mixture of monomeric (meth)acrylic acid ester of a non- tertiary alcohol having from 1 to 30 carbon atoms, other monomer or polymer or graft macromer and liquid diluents under free radical polymerization condition ADHESIVES RESEARCH, INC. 2003-05-20 US disclosed
US-5879759-A PROVIDING MACROMER AND SOLVENT-FREE RADIATION CURABLE COMPOSITION COMPRISED OF (METH)ACRYLIC ESTER OF NON-TERTIARY ALCOHOL, IRRADIATING TO FORM COATABLE SYRUP, MIXING WITH ADDITIONAL MONOMER, MULTIFUNCTIONAL MONOMER, IRRADIATING ADHESIVES RESEARCH, INC. (US) 1999-03-09 US disclosed
US-5670260-A BACKING CONTAINING URETHANE OLIGOMER ADHESIVES RESEARCH, INC. (US) 1997-09-23 US disclosed
WO-1996033247-A1 RADIATION-CURED ADHESIVE FILM HAVING DIFFERENTIAL SURFACE ADHESION ADHESIVES RESEARCH, INC. (US) 1996-10-24 WO disclosed
EP-0003845-B1 ORTHOPEDIC DEVICES, MATERIALS AND METHODS UNION CARBIDE CORPORATION (US) 1983-08-31 EP disclosed
EP-0003741-B1 RADIATION CURABLE PRESSURE SENSITIVE ADHESIVE AND PROCESS OF PREPARATION THEREOF UNION CARBIDE CORPORATION (US) 1982-12-22 EP disclosed
US-4286586-A SAID DEVICES BEING BANDAGES, CASTS, AND THE LIKE, CONTAINING A CROSSLINKED POLYLACTONE-ACRYLIC COPOLYMER UNION CARBIDE CORPORATION (US) 1981-09-01 US disclosed
US-4238522-A SPRAYING A NET WITH A COPOLYMER OF AN AMINO ACID AND A POLYHYDROXY POLYACRYLATE; CROSSLINKING POTTS JAMES E (US) 1980-12-09 US disclosed
US-4226230-A CROSSLINKED GRAFT POLYMER OF A LACTONE AND ACRYLATE UNION CARBIDE CORPORATION (US) 1980-10-07 US disclosed
EP-0003845-A1 Orthopedic devices, materials and methods UNION CARBIDE CORPORATION (US) 1979-09-05 EP disclosed
EP-0003741-A2 Radiation curable pressure sensitive adhesive and process of preparation thereof UNION CARBIDE CORPORATION (US) 1979-09-05 EP disclosed
US-4165266-A LIQUID MONOACRYLATE MONOMER AND A POLYVINYL ALKYL ETHER, QUICK STICKING UNION CARBIDE CORPORATION (US) 1979-08-21 US disclosed
US-4111769-A CARBAMYLOXYALKYL ACRYLATE, POLYOXYALKYLENE HOMO- OR COPOLYMER, PHOTOINIATOR UNION CARBIDE CORPORATION (US) 1978-09-05 US disclosed