Xanthone

Xanthone

SCHEMBL6159522

O=C(c1ccccc1)c1ccc(-c2ccccc2)cc1.O=C(c1ccccc1)c1ccccc1.O=c1c2ccccc2oc2ccccc12.[O-][S+]1c2ccccc2Cc2cc(Cl)ccc21.[O-][S+]1c2ccccc2Cc2ccccc21

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 6/20 0.40
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
ALDH1A1 P00352 4/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
POLB P06746 1/20 0.36
CNR1 P21554 1/20 0.35
MAPT P10636 3/20 0.35
NPSR1 Q6W5P4 3/20 0.35
HTT P42858 2/20 0.35
KDM4E B2RXH2 1/20 0.35
HPGD P15428 1/20 0.35
ALOX12 P18054 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
GAA P10253 1/20 0.35
KMT2A Q03164 1/20 0.35
PTPN1 P18031 1/20 0.35
ADORA3 P0DMS8 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Xanthone SCHEMBL9175425 0.77 MAOA (0.56) TTRNPC1RAB9AALDH1A1SMN1; SMN2
Xanthone SCHEMBL6402455 0.74 MAOA (0.44) TTRNPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL6070528 0.72 CYP1A2 (0.42) ALDH1A1SMN1; SMN2POLBCNR1NPSR1
SCHEMBL37076 0.72 CA1 (0.33) ALDH1A1HTTHPGDCA1CA2
Benzophenone SCHEMBL152952 0.72 ALDH1A1 (0.50) NPC1RAB9AALDH1A1SMN1; SMN2MAPT
Xanthone SCHEMBL9762833 0.69 MAOA (0.69) TTRNPC1RAB9AALDH1A1SMN1; SMN2
Anthraquinone SCHEMBL9789080 0.69 MAOA (0.43) ALDH1A1HPGDMEN1GAAKMT2A
SCHEMBL1614828 0.68 TDP2 (0.38) NPC1ALDH1A1MAPTHTTKDM4E
SCHEMBL6242650 0.67 TTR (0.77) TTRNPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL3634185 0.67 SRD5A2 (0.55) TTRALDH1A1POLBMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1504041-A1 PROCESS FOR REDUCING RESIDUAL FREE RADICAL POLYMERIZABLE MONOMER CONTENT OF POLYMERS EASTMAN CHEMICAL COMPANY (US) 2005-02-09 EP disclosed
WO-2003093328-A1 PROCESS FOR REDUCING RESIDUAL FREE RADICAL POLYMERIZABLE MONOMER CONTENT OF POLYMERS EASTMAN CHEMICAL COMPANY (US) 2003-11-13 WO disclosed