Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 13/20 | 0.48 |
| ▸ | CCR3 | P51677 | 13/20 | 0.48 |
| ▸ | FPR2 | P25090 | 2/20 | 0.43 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6397887 | 0.94 | HRH1 (0.46) | HRH1CCR3FPR2PROKR1KDM4E | |
| Ammonia Solution, Strong SCHEMBL6398869 | 0.93 | HRH1 (0.45) | HRH1CCR3FPR2PROKR1KDM4E | |
| SCHEMBL7604161 | 0.83 | HRH1 (0.58) | HRH1CCR3FPR2PROKR1KDM4E | |
| SCHEMBL7600260 | 0.81 | HRH1 (0.48) | HRH1CCR3FPR2PROKR1KDM4E | |
| SCHEMBL5102799 | 0.77 | HRH1 (0.59) | HRH1CCR3FPR2PROKR1KDM4E | |
| SCHEMBL5369447 | 0.74 | HRH1 (0.56) | HRH1CCR3FPR2PROKR1KDM4E | |
| SCHEMBL6401228 | 0.73 | HRH1 (0.47) | HRH1CCR3FPR2PROKR1KDM4E | |
| SCHEMBL6398872 | 0.73 | HRH1 (0.59) | HRH1CCR3FPR2PROKR1KDM4E | |
| SCHEMBL7518021 | 0.73 | HRH1 (0.57) | HRH1CCR3FPR2PROKR1KDM4E | |
| SCHEMBL7556424 | 0.72 | HRH1 (0.58) | HRH1CCR3FPR2PROKR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6946478-B2 | Compounds | ASTRAZENECA AB (SE) | 2005-09-20 | — | — | US | claimed |