Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1544604 | 0.84 | NPC1 (0.51) | ALDH1A1NPC1MEN1KMT2AHPGD | |
| SCHEMBL1544137 | 0.81 | HSD11B1 (0.56) | ALDH1A1KMT2AHSD11B1HSD17B10 | |
| SCHEMBL392037 | 0.81 | ALDH1A1 (0.44) | ALDH1A1NPC1MEN1KMT2AHPGD | |
| SCHEMBL4184528 | 0.81 | HSD11B1 (0.43) | ALDH1A1NPC1MEN1KMT2AHPGD | |
| SCHEMBL12803376 | 0.81 | ALDH1A1 (0.45) | ALDH1A1NPC1MEN1KMT2AHPGD | |
| SCHEMBL392717 | 0.80 | HSD11B1 (0.53) | ALDH1A1NPC1KMT2AHSD11B1RAB9A | |
| SCHEMBL11588544 | 0.79 | HSD11B1 (0.48) | ALDH1A1NPC1KMT2AHPGDHSD11B1 | |
| SCHEMBL17725100 | 0.79 | HSD17B1 (0.43) | ALDH1A1HPGDHSD11B1SMN1; SMN2MAPT | |
| SCHEMBL1543914 | 0.78 | SMN1; SMN2 (0.46) | ALDH1A1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL22728158 | 0.78 | ALDH1A1 (0.47) | ALDH1A1NPC1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | ALDH1A1 720/4885NPC1 2070/4885MEN1 3562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.