Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.54 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | KRAS | P01116 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1781653 | 1.00 | MAPT (0.59) | MAPTCYP3A4ALDH1A1KDM4EGAA | |
| SCHEMBL7838197 | 0.83 | ALDH1A1 (0.63) | MAPTCYP3A4ALDH1A1KDM4EGAA | |
| SCHEMBL6402986 | 0.82 | MAPT (0.59) | MAPTCYP3A4ALDH1A1KDM4EGAA | |
| SCHEMBL18383120 | 0.79 | MAPT (0.69) | MAPTCYP3A4ALDH1A1KDM4EGAA | |
| SCHEMBL5460837 | 0.79 | ALDH1A1 (0.44) | MAPTCYP3A4ALDH1A1KDM4EGAA | |
| SCHEMBL28115779 | 0.78 | KDM4E (0.42) | MAPTCYP3A4ALDH1A1KDM4EGAA | |
| SCHEMBL28283806 | 0.77 | CNR1 (0.55) | — | |
| SCHEMBL669111 | 0.77 | HTT (0.73) | MAPTCYP3A4ALDH1A1KDM4EGAA | |
| SCHEMBL12355450 | 0.77 | CHRNB2 (0.60) | MAPTCYP3A4ALDH1A1KDM4EGAA | |
| SCHEMBL20299611 | 0.77 | KEAP1 (0.47) | MAPTALDH1A1KDM4EGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |