Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6407962 | 0.89 | SMN1; SMN2 (0.57) | MAPTSMN1; SMN2RAB9AKDM4EPPARG | |
| SCHEMBL6405896 | 0.86 | SMN1; SMN2 (0.69) | MAPTSMN1; SMN2RAB9AKDM4EL3MBTL1 | |
| SCHEMBL6405173 | 0.84 | HPGD (0.57) | MAPTSMN1; SMN2RAB9AKDM4EL3MBTL1 | |
| SCHEMBL6406648 | 0.83 | HDAC1 (0.54) | MAPTTHRBSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL6403149 | 0.82 | NPC1 (0.57) | MAPTSMN1; SMN2RAB9AL3MBTL1NPC1 | |
| SCHEMBL6402577 | 0.82 | SMN1; SMN2 (0.72) | MAPTSMN1; SMN2RAB9AKDM4EL3MBTL1 | |
| SCHEMBL6407394 | 0.81 | LMNA (0.56) | MAPTSMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL6402396 | 0.80 | SMN1; SMN2 (0.77) | MAPTSMN1; SMN2RAB9AL3MBTL1NPC1 | |
| SCHEMBL6403008 | 0.80 | ALDH1A1 (0.54) | MAPTSMN1; SMN2RAB9ANCOR2L3MBTL1 | |
| SCHEMBL6403827 | 0.80 | POLB (0.65) | MAPTSMN1; SMN2RAB9AL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | MAPT 4543/4885THRB 2021/4885SMN1; SMN2 4458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.