Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 4/20 | 0.33 |
| ▸ | CES1 | P23141 | 4/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132364 | 0.96 | TSHR (0.67) | TSHRALDH1A1TP53LMNANFKB1 | |
| SCHEMBL2154814 | 0.92 | TSHR (0.72) | TSHRALDH1A1TP53LMNANFKB1 | |
| SCHEMBL6057425 | 0.92 | ALDH1A1 (0.61) | TSHRALDH1A1TP53LMNANFKB1 | |
| SCHEMBL6057206 | 0.92 | TSHR (0.72) | TSHRALDH1A1TP53LMNANFKB1 | |
| SCHEMBL495310 | 0.92 | TSHR (0.72) | TSHRALDH1A1TP53LMNANFKB1 | |
| SCHEMBL7329781 | 0.92 | TSHR (0.72) | TSHRALDH1A1TP53LMNANFKB1 | |
| SCHEMBL466419 | 0.92 | TSHR (0.72) | TSHRALDH1A1TP53LMNANFKB1 | |
| SCHEMBL494288 | 0.92 | TSHR (0.72) | TSHRALDH1A1TP53LMNANFKB1 | |
| Hydrochloric Acid SCHEMBL7947881 | 0.92 | TSHR (0.63) | TSHRALDH1A1TP53LMNANFKB1 | |
| SCHEMBL2154041 | 0.92 | TSHR (0.72) | TSHRALDH1A1TP53LMNANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6951905-B2 | Reacting a bisoxazolone with a diamine terminated oligomer in a solvent at a temperature of < 80 degrees c | QINETIQ LIMITED (GB) | 2005-10-04 | — | — | US | disclosed |
| US-20030158349-A1 | Bisoxazolone based polymers | QINETIQ LIMITED (GB) | 2003-08-21 | — | — | US | disclosed |