Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.79 |
| ▸ | NPC1 | O15118 | 3/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TSPO | P30536 | 1/20 | 0.53 |
| ▸ | CDK4 | P11802 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL415549 | 0.90 | RAB9A (0.74) | RAB9ANPC1KMT2ACA12CA9 | |
| SCHEMBL4072151 | 0.85 | NPC1 (0.85) | RAB9ANPC1KMT2ACA12CA9 | |
| SCHEMBL991685 | 0.85 | RAB9A (0.72) | RAB9ANPC1KMT2ACA12CA9 | |
| SCHEMBL7282371 | 0.84 | NPC1 (0.89) | RAB9ANPC1KMT2ACA12CA9 | |
| SCHEMBL12290151 | 0.84 | NPC1 (0.82) | RAB9ANPC1KMT2ACA12CA9 | |
| SCHEMBL1690816 | 0.84 | NPC1 (0.82) | RAB9ANPC1KMT2ACA12CA9 | |
| SCHEMBL4064581 | 0.84 | KMT2A (1.00) | RAB9ANPC1KMT2ACA12CA9 | |
| SCHEMBL8397202 | 0.82 | NPC1 (0.86) | RAB9ANPC1KMT2ACA12CA9 | |
| SCHEMBL4884116 | 0.82 | NPC1 (0.79) | RAB9ANPC1KMT2ACA12CA9 | |
| SCHEMBL5460753 | 0.81 | ALDH1A1 (0.54) | RAB9ANPC1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050004092-A1 | Penem derivatives and antimicrobial agent containing the same | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2005-01-06 | — | — | US | disclosed |
| EP-0757051-B1 | PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2003-10-29 | — | — | EP | disclosed |
| EP-0737232-A4 | MODULAR DESIGN AND SYNTHESIS OF AMINIMIDE CONTAINING MOLECULES | ARQULE INC (US) | 1997-11-26 | — | — | EP | disclosed |
| EP-0757051-A1 | PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1997-02-05 | — | — | EP | disclosed |
| EP-0737232-A1 | MODULAR DESIGN AND SYNTHESIS OF AMINIMIDE CONTAINING MOLECULES | ARQULE, INC. (US) | 1996-10-16 | — | — | EP | disclosed |
| WO-1995018186-A1 | MODULAR DESIGN AND SYNTHESIS OF AMINIMIDE CONTAINING MOLECULES | ARQULE PARTNERS, L.P. (US) | 1995-07-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004092-A1 | Penem derivatives and antimicrobial agent containing the same | MRPL21, MRPS2, MRPS28 | RAB9A 2939/4885NPC1 3232/4885KMT2A 2222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.