Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | GRK6 | P43250 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.38 |
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ERCC1 | P07992 | 3/20 | 0.38 |
| ▸ | FEN1 | P39748 | 3/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6404584 | 0.83 | RAB9A (0.48) | KDM4EHPGDALDH1A1NPC1RAB9A | |
| SCHEMBL6406156 | 0.80 | GRK6 (0.59) | GRK6KDM4EHPGDALDH1A1NPC1 | |
| SCHEMBL6408914 | 0.80 | ALDH1A1 (0.46) | GRK6KDM4EHPGDALDH1A1NPC1 | |
| SCHEMBL6405444 | 0.80 | ALDH1A1 (0.39) | KDM4EHPGDALDH1A1NPC1RAB9A | |
| SCHEMBL16171148 | 0.79 | MEN1 (0.54) | GRK6KDM4EHPGDALDH1A1NPC1 | |
| SCHEMBL6406188 | 0.79 | ALDH1A1 (0.40) | KDM4EHPGDALDH1A1NPC1RAB9A | |
| SCHEMBL6410721 | 0.78 | BCAT1 (0.40) | GRK6KDM4EHPGDALDH1A1NPC1 | |
| SCHEMBL6403770 | 0.77 | SMN1; SMN2 (0.44) | KDM4EHPGDALDH1A1NPC1RAB9A | |
| SCHEMBL6408592 | 0.77 | NPC1 (0.49) | KDM4EHPGDALDH1A1NPC1RAB9A | |
| SCHEMBL6403222 | 0.76 | GRK6 (0.35) | GRK6KDM4EHPGDALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | ADORA3 141/4885ADORA2B 591/4885ADORA1 486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.