Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1702862 | 0.80 | ALDH1A1 (0.56) | KMT2AMEN1ALDH1A1RAB9ATDP1 | |
| SCHEMBL6406118 | 0.74 | TDP1 (0.73) | KMT2AMEN1GAAPKMALDH1A1 | |
| SCHEMBL4215049 | 0.73 | ALDH1A1 (0.64) | ALDH1A1RAB9ACYP1A2MAPTSMN1; SMN2 | |
| SCHEMBL4207071 | 0.71 | PTGES (0.72) | KMT2AMEN1PKMALDH1A1CYP1A2 | |
| SCHEMBL4207324 | 0.69 | ALDH1A1 (0.62) | KMT2AMEN1PKMALDH1A1RAB9A | |
| SCHEMBL4197175 | 0.69 | KMT2A (0.67) | KMT2AMEN1GAAPKMALDH1A1 | |
| SCHEMBL1755253 | 0.69 | TP53 (0.65) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| SCHEMBL4368613 | 0.68 | ALDH1A1 (0.61) | KMT2AMEN1GAAPKMALDH1A1 | |
| SCHEMBL15507864 | 0.67 | ALDH1A1 (0.66) | KMT2AMEN1GAAPKMALDH1A1 | |
| SCHEMBL1702962 | 0.67 | ALDH1A1 (0.66) | KMT2AMEN1GAAPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | KMT2A 2263/4885MEN1 3562/4885GAA 85/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.