Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | GRK2 | P25098 | 1/20 | 0.42 |
| ▸ | SLC5A7 | Q9GZV3 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6407917 | 0.85 | RAB9A (0.52) | RAB9ASMN1; SMN2ALDH1A1GAAHPGD | |
| SCHEMBL6407737 | 0.76 | HDAC6 (0.49) | SMN1; SMN2ALDH1A1GAAHPGDHDAC6 | |
| SCHEMBL6403162 | 0.75 | POLB (0.54) | RAB9ASMN1; SMN2ALDH1A1HPGDHDAC6 | |
| SCHEMBL6404220 | 0.74 | KMT2A (0.50) | RAB9ASMN1; SMN2ALDH1A1HDAC6MEN1 | |
| SCHEMBL6407614 | 0.73 | KMT2A (0.54) | RAB9ASMN1; SMN2HDAC6MEN1KMT2A | |
| SCHEMBL6404893 | 0.72 | ROCK2 (0.56) | RAB9ASMN1; SMN2ALDH1A1HPGDHDAC6 | |
| SCHEMBL6404881 | 0.72 | SLC5A7 (0.59) | RAB9ASMN1; SMN2SLC5A7NPC1 | |
| SCHEMBL6402278 | 0.72 | HDAC6 (0.57) | RAB9ASMN1; SMN2ALDH1A1HDAC6LMNA | |
| SCHEMBL6404124 | 0.72 | POLB (0.69) | RAB9ASMN1; SMN2ALDH1A1GAALMNA | |
| SCHEMBL6409325 | 0.72 | NPC1 (0.64) | RAB9ASMN1; SMN2ALDH1A1HPGDHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050166938-A1 | Device for treating keratin fibers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2005-08-04 | — | — | US | disclosed |
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | RAB9A 4044/4885SMN1; SMN2 4458/4885ALDH1A1 1486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.