Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A7 | Q9GZV3 | 5/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6404881 | 0.88 | SLC5A7 (0.59) | SLC5A7GABRA5NPC1SMN1; SMN2ATM | |
| SCHEMBL6403162 | 0.79 | POLB (0.54) | HDAC6NPC1SMN1; SMN2RAB9APOLB | |
| SCHEMBL8187667 | 0.78 | MAPT (0.41) | SLC5A7SMN1; SMN2ATM | |
| SCHEMBL6403886 | 0.77 | SLC5A7 (0.53) | SLC5A7GABRA5NPC1SMN1; SMN2ATM | |
| SCHEMBL6408017 | 0.76 | SMN1; SMN2 (0.53) | SLC5A7GABRA5NPC1SMN1; SMN2ATM | |
| SCHEMBL6404220 | 0.75 | KMT2A (0.50) | HDAC6NPC1SMN1; SMN2RAB9APOLB | |
| SCHEMBL6410047 | 0.74 | RAB9A (0.59) | SLC5A7GABRA5NPC1SMN1; SMN2RAB9A | |
| SCHEMBL6407737 | 0.74 | HDAC6 (0.49) | HDAC6NPC1SMN1; SMN2POLB | |
| SCHEMBL6402278 | 0.73 | HDAC6 (0.57) | HDAC6NPC1SMN1; SMN2RAB9APOLB | |
| SCHEMBL6409325 | 0.72 | NPC1 (0.64) | HDAC6NPC1SMN1; SMN2RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | SLC5A7 3816/4885GABRA5 415/4885HDAC6 2320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.