Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.51 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | LIPC | P11150 | 2/20 | 0.51 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.48 |
| ▸ | SLC5A7 | Q9GZV3 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6405901 | 0.84 | LMNA (0.61) | SMN1; SMN2ERCC1ERCC4LMNA | |
| SCHEMBL6407440 | 0.80 | EPHX2 (0.57) | SMN1; SMN2ATMEPHX2LIPCLIPG | |
| SCHEMBL6410124 | 0.79 | SMN1; SMN2 (0.52) | SMN1; SMN2ATMEPHX2LIPCLIPG | |
| SCHEMBL6403571 | 0.76 | SLC5A7 (0.48) | SMN1; SMN2ATMEPHX2GABRA5SLC5A7 | |
| SCHEMBL28946362 | 0.73 | ERCC1 (0.70) | ERCC1ERCC4 | |
| SCHEMBL5804315 | 0.73 | ERCC1 (0.70) | ERCC1ERCC4 | |
| SCHEMBL9548380 | 0.70 | SMN1; SMN2 (0.46) | SMN1; SMN2ATMEPHX2LMNARAB9A | |
| SCHEMBL6402251 | 0.69 | NPC1 (0.54) | SMN1; SMN2EPHX2GABRA5SLC5A7LMNA | |
| SCHEMBL10138151 | 0.69 | PKM (0.58) | ERCC1ERCC4LMNA | |
| SCHEMBL19523017 | 0.69 | PKM (0.58) | ERCC1ERCC4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | SMN1; SMN2 4458/4885ATM 1728/4885ERCC1 3109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.