Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6402261 | 0.86 | HPGD (0.53) | SMN1; SMN2HPGDPOLBRAB9AALDH1A1 | |
| SCHEMBL6410595 | 0.85 | HPGD (0.51) | SMN1; SMN2HPGDMAPTRAB9AALDH1A1 | |
| SCHEMBL6404892 | 0.85 | EPHX2 (0.37) | SMN1; SMN2HPGDPOLBMAPTRAB9A | |
| SCHEMBL6403795 | 0.84 | SMN1; SMN2 (0.39) | SMN1; SMN2HPGDPOLBMAPTRAB9A | |
| SCHEMBL6407810 | 0.83 | HPGD (0.57) | HPGDPOLBMAPTHDAC1HDAC7 | |
| SCHEMBL6407737 | 0.82 | HDAC6 (0.49) | SMN1; SMN2HPGDPOLBHDAC1ALDH1A1 | |
| SCHEMBL6401603 | 0.80 | ALDH1A1 (0.40) | SMN1; SMN2HPGDPOLBRAB9AALDH1A1 | |
| SCHEMBL6406614 | 0.80 | NAMPT (0.48) | SMN1; SMN2POLBRAB9ANPC1LMNA | |
| SCHEMBL6406674 | 0.79 | HPGD (0.58) | SMN1; SMN2HPGDPOLBMAPTHDAC1 | |
| SCHEMBL6405928 | 0.79 | MAPK1 (0.52) | SMN1; SMN2HPGDPOLBMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | SMN1; SMN2 4458/4885HPGD 3244/4885POLB 3713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.