Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6403980 | 0.85 | SMN1; SMN2 (0.55) | SMN1; SMN2POLBMAPTHPGDALDH1A1 | |
| SCHEMBL6403795 | 0.84 | SMN1; SMN2 (0.39) | EPHX2SMN1; SMN2POLBMAPTHPGD | |
| SCHEMBL6401603 | 0.80 | ALDH1A1 (0.40) | EPHX2SMN1; SMN2POLBHPGDALDH1A1 | |
| SCHEMBL6406614 | 0.79 | NAMPT (0.48) | EPHX2SMN1; SMN2POLBL3MBTL1THRB | |
| SCHEMBL6402261 | 0.78 | HPGD (0.53) | SMN1; SMN2POLBHPGDALDH1A1NPC1 | |
| SCHEMBL6404146 | 0.77 | EPHX2 (0.43) | EPHX2SMN1; SMN2POLBMAPTALDH1A1 | |
| SCHEMBL6410595 | 0.77 | HPGD (0.51) | SMN1; SMN2MAPTHPGDALDH1A1HTT | |
| SCHEMBL6410105 | 0.77 | HPGD (0.54) | SMN1; SMN2POLBMAPTHPGDALDH1A1 | |
| SCHEMBL6406674 | 0.76 | HPGD (0.58) | EPHX2SMN1; SMN2POLBMAPTHPGD | |
| SCHEMBL6407737 | 0.76 | HDAC6 (0.49) | SMN1; SMN2POLBHPGDALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | EPHX2 2961/4885SMN1; SMN2 4458/4885POLB 3713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.