Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.64 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anisole SCHEMBL415394 | 0.91 | CA4 (0.70) | CA4LTA4HCES2CES1PKM | |
| Anisole SCHEMBL1873043 | 0.91 | CA4 (0.70) | CA4LTA4HCES2CES1PKM | |
| Anisole SCHEMBL25392752 | 0.88 | CA4 (0.67) | CA4LTA4HCES2CES1PKM | |
| Anisole SCHEMBL29973795 | 0.88 | CA4 (0.67) | CA4LTA4HCES2CES1PKM | |
| Anisole SCHEMBL7165189 | 0.88 | CA4 (0.67) | CA4LTA4HCES2CES1PKM | |
| Anisole SCHEMBL9269922 | 0.88 | CA4 (0.67) | CA4LTA4HCES2CES1PKM | |
| 1,4-Dimethoxybenzene SCHEMBL3855313 | 0.88 | PKM (0.58) | CES2CES1PKMCA1CA2 | |
| Anisole SCHEMBL10674071 | 0.87 | CA4 (0.58) | CA4LTA4HCES2CES1PKM | |
| Anisole SCHEMBL6771858 | 0.86 | CA4 (0.64) | CA4LTA4HCES2CES1PKM | |
| Anisole SCHEMBL27905059 | 0.86 | CA4 (0.64) | CA4LTA4HCES2CES1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119805-B2 | Substituted disulfonamide compounds | GRUENENTHAL GMBH (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20100152158-A1 | Substituted Disulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2010-06-17 | — | — | US | disclosed |
| EP-0510526-B1 | Use of sulfonamides as drug and new sulfonamides | HOFFMANN LA ROCHE (CH) | 1996-12-04 | — | — | EP | disclosed |
| EP-0510526-A1 | Use of sulfonamides as drug and new sulfonamides | F.HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1992-10-28 | — | — | EP | disclosed |
| EP-0221344-B1 | SULPHONYL-PHENYL ALKYL AMINES, PROCESS FOR THEIR PREPARATION AND MEDICINES | Roche Diagnostics GmbH (DE) | 1990-05-23 | — | — | EP | disclosed |
| EP-0221344-A1 | Sulphonyl-phenyl alkyl amines, process for their preparation and medicines | Roche Diagnostics GmbH (DE) | 1987-05-13 | — | — | EP | disclosed |
| EP-0093363-B1 | PROCESS FOR THE PREPARATION OF DISULPHIDES | CASSELLA Aktiengesellschaft (DE) | 1987-01-14 | — | — | EP | disclosed |
| EP-0059241-B1 | PROCESS FOR PREPARING AROMATIC SULFONYL HALOGENIDES | BASF Aktiengesellschaft (DE) | 1986-01-29 | — | — | EP | disclosed |
| US-4464537-A | Preparation of saccharin | BASF AKTIENGESELLSCHAFT (DE) | 1984-08-07 | — | — | US | disclosed |
| EP-0052750-B1 | PROCESS FOR THE PREPARATION OF SACCHARIN | BASF Aktiengesellschaft (DE) | 1984-03-28 | — | — | EP | disclosed |
| EP-0031954-B1 | SULPHONAMIDES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1984-03-14 | — | — | EP | disclosed |
| EP-0093363-A1 | Process for the preparation of disulphides | CASSELLA Aktiengesellschaft (DE) | 1983-11-09 | — | — | EP | disclosed |
| EP-0059241-A1 | Process for preparing aromatic sulfonyl halogenides | BASF Aktiengesellschaft (DE) | 1982-09-08 | — | — | EP | disclosed |
| EP-0052750-A1 | Process for the preparation of saccharin | BASF Aktiengesellschaft (DE) | 1982-06-02 | — | — | EP | disclosed |
| EP-0031954-A2 | Sulphonamides, process for their preparation and medicines containing these compounds | Roche Diagnostics GmbH (DE) | 1981-07-15 | — | — | EP | disclosed |
| EP-0002680-B1 | 4-SPECTINOMYCYLAMIN AND ITS PHYSIOLOGICALLY ACCEPTABLE SALTS, METHOD OF PREPARATION AND PHARMACEUTICAL PRODUCTS CONTAINING THESE SUBSTANCES | Dr. Karl Thomae GmbH (DE) | 1981-02-11 | — | — | EP | disclosed |
| EP-0002680-A2 | 4-Spectinomycylamin and its physiologically acceptable salts, method of preparation and pharmaceutical products containing these substances | Dr. Karl Thomae GmbH (DE) | 1979-07-11 | — | — | EP | disclosed |
| US-4039511-A | Process for the manufacture of polyethers from bisphenates and sulfonyl halides | BASF AKTIENGESELLSCHAFT (DT) | 1977-08-02 | — | — | US | disclosed |
| US-3932419-A | QUINOLINE DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152158-A1 | Substituted Disulfonamide Compounds | BDKRB1, BDKRB2, BRS3 | CA4 2472/4885LTA4H 1220/4885CES2 1954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.